高纯度药物中间体孕烯雌酚CAS：145-13-1
快速详细信息：
描述：
孕烯醇酮及其硫酸盐及其硫酸盐和孕酮属于在大脑某些区域发现高浓度的神经甾体类，并在那里合成。神经类固醇影响突触功能，是神经保护，并增强髓磷脂化。怀孕烯龙醇及其硫酸酯正在研究中，以提高认知和记忆功能的潜力。孕烯醇酮也被认为是精神分裂症的潜在治疗方法。
有趣的是，不同于孕烯醇酮，硫酸孕烯雌酚是GABA A受体的负变构调节剂，也是NMDA受体的正变构调节剂。此外，已经显示激活肝细胞中的瞬时受体电位M3（TRPM3）离子通道和导致钙进入和随后的胰岛素释放的胰岛。
由大脑产生的分子，孕烯醇酮作为抵抗动物效应的自然防御机制。孕烯醇酮可阻止THC /（主要活性成分）完全活化其脑受体CB1受体，当被THC引起过度刺激时会引起令人反感的效果
应用：
孕烯醇酮用于疲劳和增加能量;阿尔茨海默病和增强记忆力;创伤和伤害;以及压力和提高免疫力。
它也用于皮肤病，包括牛皮癣和硬皮病。
妇女使用孕烯醇代谢块状乳房（纤维囊性乳腺疾病），子宫内膜障碍（子宫内膜异位症），更年期症状和经前综合征（PMS）。
有些人使用孕烯醇酮来减缓或逆转老化，关节炎和抑郁。它还用于加强心脏，过敏反应，“解毒”，狼疮，多发性硬化（MS），前列腺问题和癫痫发作。癫痫发作。

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High Purity Pharmaceutical Intermediate Powder Pregnenolone CAS: 145-13-1
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Description:
Pregnenolone and its sulfate, likeand its sulfate and progesterone, belong to the group of neurosteroids that are found in high concentrations in certain areas of the brain, and are synthesized there. Neurosteroids affect synaptic functioning, are neuroprotective, and enhance myelinization. Pregnenolone and its sulfate ester are under investigation for their potential to improve cognitive and memory functioning. Pregnenolone is also being considered as a potential treatment for schizophrenia.
Interestingly, unlike pregnenolone, pregnenolone sulfate is a negative allosteric modulator of the GABAA receptor as well as a positive allosteric modulator of the NMDA receptor. In addition, it has been shown to activate the transient receptor potential M3 (TRPM3) ion channel in hepatocytes and pancreatic islets causing calcium entry and subsequent insulin release.
Pregnenolone, a molecule produced by the brain, acts as a natural defense mechanism against effects in animals. Pregnenolone prevents THC/, the main active principle in , from fully activating its brain receptor, the CB1 receptor, that when overstimulated by THC/causes the intoxicating effects
Application:
Pregnenolone is used for fatigue and increasing energy; Alzheimer's disease and enhancing memory; trauma and injuries; as well as stress and improving immunity.
It is also is used for skin disorders including psoriasis and scleroderma.
Women use pregnenolone for lumpy breasts (fibrocystic breast disease), a disorder of the lining of the uterus (endometriosis), symptoms of menopause, andpremenstrual syndrome (PMS).
Some people use pregnenolone for slowing or reversing aging, arthritis, anddepression. It is also used for strengthening the heart, allergic reactions, 'detoxification,' lupus, multiple sclerosis (MS), prostate problems, and seizures.d seizures.

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