SR9011 99％高品质CAS 1379686-30-2健身
产品描述
产品名称：SR9011
Cas No .: 1379686-29-9
同义词：3 - （（（（4-氯苄基）（（5-硝基噻吩-2-基）甲基）氨基）甲基）-N-戊基吡咯烷-1-甲酰胺
分子式：C23H31ClN4O3S
Molucelar重量：479.03524
包装：铝箔袋或根据需要
化学名称：3 - （（（（4-氯苄基）（（5-硝基噻吩-2-基）甲基）氨基）甲基）-N-戊基吡咯烷-1-酮
-1-甲酰胺
SR9011说明及应用：
SR9011是一种三官能的甲基丙烯酸酯单体，可与金属基材提供卓越的附着力。
SR9011推荐用于过氧化物固化涂料，密封剂和PVC基增塑溶胶。
建议使用量为5％至10％。
描述：
SR9011是一种三官能的甲基丙烯酸酯单体，可与金属基材提供卓越的附着力。 SR9011推荐用于过氧化物固化涂料，密封剂和PVC基增塑溶胶。推荐使用5％至10％重量的使用量.R9011是一种强效和特异性的合成REV-ERB激动剂，与EC50〜790nM和REV-ERB-结合，具有EC50〜560nM的REV-ERB-。
它还具有良好的体内血浆/脑暴露。核受体REV-ERB-和REV-ERB-在调节核心时钟蛋白的表达，促进活动和代谢中的节律中起着不可或缺的作用。 SR9011的施用改变了小鼠下丘脑中昼夜节律行为和核心时钟基因表达的昼夜节律模式。肝脏，骨骼肌和脂肪组织中一系列代谢基因的昼夜节律表达模式也发生改变，导致能量消耗增加。
用SR9011处理饮食诱导的肥胖小鼠通过减少脂肪量降低肥胖，明显改善血脂异常和高血糖。这些结果表明，药理学靶向昼夜节律的合成REV-ERB配体可能有益于治疗睡眠障碍以及代谢性疾病。

产品用途：
SR9011以类似于在耐力训练的动物中观察到的变化的方式改变骨骼肌的代谢特征。基本上，药物向肌肉发出信号，告诉它修改其新陈代谢。研究的一半小鼠在时间和距离方面表现出改善的运行耐力。显而易见的是，一个小的药物样分子可以增加骨骼肌的代谢率，增加运动耐力SR9011不仅仅是一种“饮食”药丸;丸。
没有办法糖衣 - 虽然许多人尝试 - 保持健康的体重可能是困难的。因为很难，许多人尝试了“奇迹”减肥药和其他快速修复，最终需要改变生活方式。许多非处方饮食和减肥药是不受管制的，可能含有危险成分。然而，SR9011不像食欲抑制剂，泻药或“脂肪阻滞剂”。而您不会在蛋白质粉末或运动补充剂的成分列表中找到SR9011。
SR9009与其他减肥药的区别在于其化学成分.R9011不是食欲抑制因子，因为许多减肥药物 - 通过增加肌肉的代谢率直接起作用。你的新陈代谢在白天加速和自然减慢，这意味着有时食物被用于能量，有时它被储存为脂肪。通过重新同步功能异常的代谢时钟，SR9011确保食物和多余的脂肪被用作能量。
SR9011是Burris和他的团队在TSRI开发的一种化合物之一。该药物与Rev-erb结合，Rev-erb是体内影响肝脏中脂质和葡萄糖代谢，炎症反应和脂肪储存细胞的天然蛋白质。通过结合Rev-erb，SR9011可以通过另一种令人愉快的副作用来启动新陈代谢：增加肌肉力量。

SR9011 99% High Quality CAS 1379686-30-2 for bodybuilding
Product Description
Product Name: SR9011
Cas No.: 1379686-29-9
Synonyms: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide
Formula: C23H31ClN4O3S
Molucelar weight: 479.03524
Packing:foil bag or as required
Chemical Name: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-
1-carboxamide
SR9011 Description and Applications:
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols.
Usage levels of 5% to 10% by weight are recommended.
Description:
SR9011 is a trifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB- with an EC50 ~790 nM and REV-ERB-with EC50 ~560 nM.
It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB- and REV-ERB- play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

Product Usage:
SR9011 alters the metabolic profile of skeletal muscle in a manner similar to the changes observed in animals that are endurance trained. Basically, the drug sends a signal to the muscle to tell it to modify its metabolism. Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that a small, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance SR9011 Not Just a 'Diet' Pill.quot; Pill.
There's no way to sugarcoat it-though many have tried-maintaining a healthy weight can be difficult. Because it's hard, many have tried 'miracle' weight-loss pills and other quick fixes for something that ultimately requires a lifestyle change. Many over-the-counter diet and weigh-loss pills are unregulated and may contain dangerous ingredients. SR9011, however, isn't like appetite suppressants, laxatives, or 'fat blockers.' And you won't find SR9011 in the ingredient lists of protein powders or exercise supplements.exercise supplements.
The difference between SR9009 and other diet pills is in its chemistry.SR9011 is not an appetitesuppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching a dysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy.
SR9011 is one of a pair of compounds developed at TSRI by Burris and his team. The drug binds to Rev-erb,a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells. By binding to Rev-erb, SR9011 can kickstart metabolism with another pleasant side-effect: increased muscle strength.