Sunifiram 314728-85-3 Dm-235 White Powder Pharmaceutical Raw Material Fitness Supplement
Sunifiram 314728-85-3 Dm-235白粉药用原料健身补充剂
议价
加入意向| 型号。 | 314728-85-3 |
| 定制 | 非定制 |
| 适合 | 成人 |
| 纯度 | >99% |
| 出现 | 白色粉末 |
| 付款条件 | 西联汇款，Moneygram，T / T，比特币 |
| 规范 | gmp，sgs，iso，kosher |
| HS编码 | 6809900000 |
| 粉末 | 是 |
| 证明 | gmp，iso 9001，usp，bp |
| 州 | 固体 |
| 产品名称 | Sunifiram |
| 功能 | 增强心理智力 |
| 商标 | whsm |
| 起源 | 中国 |
生激素粉，类固醇粉源
Sunifiram 314728-85-3 DM-235白色粉末药物原料健身补品
产品描述
产品名称Sunifiram（DM-235）
同义1-苯甲酰基-4-丙酰基哌嗪
分子式：C14H18N2O2
分子量：246.304
CAS：314728-85-3
纯度：99.8％
熔点：94.5℃-95.5℃95.5℃g;C95.5°C
外观：白色至白色结晶性粉末
付款方式：T / T，西联汇款和钱币
交货：付款后24小时内
快递：EMS，DHL，FedEx等（门到门）
介绍：
Sunifiram（DM-235）是哌嗪衍生的ampakine药物，其作为AMPA受体的正变构调节剂，并且在动物研究中具有明显高于吡乙酰胺效力的益智效应。许多相关的化合物是已知的，最着名的是单链脲（DM-232）。
sunifiram的这种增强与通过激活蛋白激酶II（CaMKII）的AMPAR磷酸化的增加和通过激活蛋白激酶Cα（PKCα）的NMDAR磷酸化的增加相关联。更具体地，sunifiram通过Src激酶刺激NMDAR的甘氨酸结合位点并伴随PKCα活化。 PKCα活性的增强触发通过CaMKII激活增强海马LTP。 Sunifiram通过CaM激酶II和蛋白激酶C激活促进认知缺陷。蛋白激酶C活化。tein kinase C activation.
Sunifiram（DM-235）是一种合成衍生物 吡拉西坦虽然由于破坏了吡咯烷酮骨架，但不再存在 西坦 一类药物（但通过衍生自这些药物，仍然通常与该类有关）。
Sunifiram具有类似的机制 奈非西坦 在海马中，类似于该药物，sunifiram显示抗失忆性质，并且潜在地是认知增强剂。其抗惊厥活性比吡拉西坦在每重量基础上高出几个数量级，初步证据表明它具有类似的低毒性。
这种化合物被称为AMPAkine，因为它通过AMPA受体（谷氨酸受体的三个主要亚型，NDMA和红藻氨酸盐一起）发挥其大部分作用。 AMPA功能的这种增强似乎也依赖于通过增强信号传递 甘氨酸 NMDA受体的结合位点，尽管一个最小的信号通过NMDA受体，然而AMPA受体的益处似乎是剂量依赖性的。
由于有限的证据，确定晒黑的最佳剂量是非常困难的，但是由于1mg / kg已被确定为对小鼠和大鼠均有好处，因此给予0.08-0.16mg / kg的预先人剂量（对于150μl人，5.4-11mg）。
功能：
Sunifiram激活AMPA介导的神经传递。
以钟形剂量反应关系增强LTP。
Sunifiram有助于大脑皮质中释放乙酰胆碱。
Sunifiram提高能量水平，使用户感觉到更有动力和消除
Sunifiram增加浓度水平增加，用户感觉到外界刺激分心。
Sunifiram也增强了长期增效，这是形成关于存储器存储的新连接。
Sunifiram有一些抗焦虑的好处。感觉更放松是有益的，当试图集中精力。
Sunifiram剂量：
如上所述，成年人的典型剂量为约5mg的sunifiram。当舌下舌下（即舌下）而不是吞咽它时，效果的强度更大。不要太担心，如果你超过标准剂量，虽然！ Sunifiram具有极低的毒性，治疗和危险量之间有很大的差距。
竞争优势：
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武汉胡梅是着名的制药企业，专业从事大陆原料类固醇粉末。中国中心地区不仅是类固醇粉末和药物原料的领先制造商，还出口到世界各地。所有粉末均由工厂直接供应。
我们的产品已经出口到德国，挪威，波兰，芬兰，西班牙，英国，法国，俄罗斯，美国，巴西，墨西哥，澳大利亚，日本，韩国，泰国，印度尼西亚，乌拉圭等许多国家。月产量超过100kg。我们珍惜在健身房，运动员领域，医疗机构，诊所等方面服务的大量忠实客户
最优质的产品，最具竞争力的价格。灵活和不可追溯的付款条件。独家客户服务和24/7网络及时有帮助的售后服务。
- 贝蒂·威廉姆斯
- Momi Wilson
- 海富克
| Model NO. | 314728-85-3 |
| Customized | Non-Customized |
| Suitable for | Adult |
| Purity | >99% |
| Appearance | White Powder |
| Payment Terms | Western Union, Moneygram, T/T, Bitcoin |
| Specification | GMP, SGS, ISO, KOSHER |
| HS Code | 6809900000 |
| Powder | Yes |
| Certification | GMP, ISO 9001, USP, BP |
| State | Solid |
| Product Name | Sunifiram |
| Function | Enhance Mental Intelligence |
| Trademark | WHSM |
| Origin | China |
raw hormone powders,steroid powder source
Sunifiram 314728-85-3 DM-235 White Powder Pharmaceutical Raw Material Fitness Supplement
Product Description
Product Name Sunifiram (DM-235)
Synony 1-benzoyl-4-propanoylpiperazine
Molecular Formul:C14H18N2O2
Molecular Weight:246.304
CAS:314728-85-3
Purity :99.8%
Melting point:94.5°C-95.5°C95.5°Cg;C95.5°C
Appearance:Off-white to white crystalline powder
Payment:T/T, Western Union and Money Gram
Delivery:Within 24hours After Your Payment
Express: EMS, DHL, FedEx, etc(door-to-door)
Introduction:
Sunifiram (DM-235) is a piperazine derived ampakine drug which acts as a positive allosteric modulator of AMPA receptors, and has nootropic effects in animal studies with significantly higher potency than piracetam. A number of related compounds are known, the best known being unifiram (DM-232).
This enhancement by sunifiram is associated with an increase inphosphorylation of AMPAR through activation of protein kinase II(CaMKII) and an increase in phosphorylation of NMDAR through activation of protein kinase C α (PKCα). More specifically, sunifiram stimulates the glycine-binding site of NMDAR with concomitant PKCαactivation through Src kinase. Enhancement of PKCα activity triggers to potentiate hippocampal LTP through CaMKII activation. Sunifiram improves cognitive deficits via CaM kinase II andprotein kinase C activation.tein kinase C activation.tein kinase C activation.
Sunifiram (DM-235) is a synthetic derivative of Piracetam, although due to breaking the pyrrolidone backbone it is no longer in the Racetam class of drugs (yet by being derived from them, it is still commonly associated with this class).
Sunifiram has mechanisms similar to Nefiracetam in the hippocampus, and similar to that drug sunifiram shows anti-amnesiac properties and is potentially a cognitive enhancer. Its anti-amnesiac activity is several orders of magnitude greater than piracetam on a per weight basis, and preliminary evidence suggest it has a similarly low toxicity profile.
This compound is known as an AMPAkine due to exerting most of its actions via the AMPA receptor (one of the three main subsets of glutamate receptors, alongside NDMA and kainate). This enhancement of AMPA function seems to also rely on enhancing signalling via the Glycine binding site of NMDA receptors, although one minimal signalling goes through the NMDA receptor then the benefits on AMPA receptors seem dose-dependent.
It is very hard to determine an optimal dose for sunifiram due to such limited evidence, but since 1mg/kg has been determined to be good for both mice and rats this gives a preliminary human dose of 0.08-0.16mg/kg (for a 150lb person, 5.4-11mg).
Function:
Sunifiram activates AMPA-mediated neurotransmission.
Enhancing LTP in a bell-shaped dose-response relationship.
Sunifiram aids in the release of acetylcholine in the cerebral cortex.
Sunifiram increases energy levels, allowing users to feel more motivated and eliminate
Sunifiram increase Levels of concentration increase, and users feel less distracted by external stimuli.
Sunifiram also enhances long-term potentiation, which is the forming of new connections regarding memory storage.
Sunifiram has some anxiolytic benefits. Feeling more relaxed is beneficial when trying to focus.
Sunifiram DOSING:
Like what was mentioned above, the typical dose for an adult human would be approximately 5mg of sunifiram. The strength of the effects are greater when it is taken sublingually (i.e. under the tongue) as opposed to just swallowing it. Don't worry too much if you go over the standard dose, though! Sunifiram has extremely low toxicity and a huge range between therapeutic and dangerous amounts.
Competitive Advantage:
1 High quality with competitive price:
1) Standard: Enterprise Standard
2) All Purity≥98%;98%;98%
3) We are manufacturer and can provide high quality products with factory price.
2 Fast and safe delivery:
1) Parcel can be sent out in 24 hours after payment. Tracking number available
2) Secure and discreet shipment. Various transportation methods for your choice.
3) Customs pass rate ≥99%;99%;99%
4) We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
How to proceed order:
First: Please let me know the items you are looking for, quantity, and the destination country.
Second: You confirm all details, and offer us purchasing order;
Third: We send the detail price of our product and offer the suitable shipping method for reference.
Forth: You confirm the order and pay money 100% in advance and send us the detail address.
Fifth: We arrange the shipment according to your requirements.
Sixth: We offer after-sales service after you receive parcel
wuhanshumai is a renowned pharmaceutical manufacturer, specializing in raw steroid powders in Mainland China. It is not only the leading manufacturer of steroids powder and pharmaceutical raw materials in the central area of China but also exports all over the world. All powders are factory directly supplying.
Our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries. Monthly output is over 100kgs. We cherish a great number of loyal customers serving in gym fields, athletes fields , medical institution ,clinics and so on
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