理想口腔粉末枪YK11 CAS 431579-34-9用于健美
基本细节：
产品名称：YK11
cas：431579-34-9
MF：C152h252n44o42
mw：3367.2
纯度：99.0％
外观：白色粉末
描述：
YK-11 Sarm是合成类固醇，具有合成代谢和未被发现的孕激素潜力。
该产品具有与类固醇相同的骨架。选择性雄激素受体调节剂给予用户与其他类固醇相同的生长肌肉结果，没有任何负面的副作用。
该物质具有与肌生成抑制素相似的作用的能力。日本的科学家们继续做实验以发现更多的类固醇
什么是YK11？
YK11是地下灰色市场健美补充世界当月的最新风味。 YK11是一种类固醇分子，仅在细胞测定中才有效果。这意味着还没有在动物或人类中发表任何结果。即使如此，它已经出现在互联网上作为合成代谢的SARM或选择性雄激素受体调节剂。
新型SARD如LGD-4033和Ostarine是非甾体类，这意味着它们没有典型的四环结构的经典雄激素类固醇可以被认为是SARM，因为它们将5-α还原转化为较不有效的雄激素，合理的剂量比雄激素效应显示出更多的合成代谢。类固醇已经变成一个坏话，因此大多数情况下，公司正在开发非甾体类SARMS。实际上，分子的形状几乎没有什么区别，而是它的作用。
YK11是甾体。事实上，这两篇文章可以看出，YK11可以激活雄激素受体，但它只能部分地发挥作用。这导致称为部分激动作用的效果。这意味着YK11可能会替代更强的雄激素，同时对受体产生更低的总体刺激作用。事实上，Kanno等人的文章通过在DHT单独或DHT + YK11中洗涤细胞来证明这种效应。那些接受DHT和YK11的细胞与单独的DHT相比，具有较少的雄激素刺激。这是重要的，因为在更强壮的雄激素的存在下，YK11将实际上减少雄激素受体刺激。在前列腺或毛囊的情况下，这可能是一件好事。在骨骼肌中，这不是一件好事。
由于YK11在动物或人类中的作用尚未发表，所以人们猜测会有什么影响。我们甚至不知道这种分子是否具有口服的生物利用度，但是由于它是类固醇，所以很可能不是。此外，由于它是部分激动剂，所以没有理由相信在具有正常水平的睾酮的人中将是合成代谢。最后，我们不知道这个分子甚至是远程安全的。它是否提高肝脏酶，是否具有遗传毒性或致癌性？新药经过严格的毒理学检查，以确保其安全。据我所知，至少从文学角度来看，YK11并没有这样做。这个化合物有太多的未知数甚至考虑使用它。
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Ideal Oral powder sarms YK11 CAS 431579-34-9 for Bodybuilding
Basic Details:
Product Name: YK11
CAS: 431579-34-9
MF : C152h252n44o42
MW : 3367.2
Purity: 99.0%
Appearance: White Powder
Description:
YK-11 Sarm is a synthetic steroid with anabolic as well as undiscovered progestin potential.
The product has the same backbone like the steroids. The selective androgen receptor modulator gives users the same growth muscles results as other steroids without any negative side effects.
The substance has the ability of producing the similar effects as myostatin. Japanese scientists have continued to do experiments to discover more about the steroid
What is YK11 ?
YK11 is the latest flavor of the month in the underground gray market bodybuilding supplement world. YK11 is a steroidal molecule that has only been shown to have effects in cellular assays. This means that there are no published results in animals or humans as yet. Even so it has popped up for sale on the internet as an anabolic SARM or Selective Androgen Receptor Modulator.
New age SARMs like LGD-4033 and Ostarine are non-steroidal, meaning that they do not have the typical four ring structure of classical androgens Steroids can be considered to be SARMs since they convert through 5-alpha reduction to less potent androgens and in reasonable doses show more anabolic than androgenic effects. Steroid has been turned into a bad word so for the most part, companies are developing non-steroidal SARMS. In reality, it makes little difference the shape of the molecule but rather what its effects are.
YK11 is steroidal. In fact,The two papers that are available show that YK11 can activate the androgen receptor but that it does so only partially. This results in an effect known as partial agonism. This means that YK11 can potentially displace stronger androgens while exerting a lower overall stimulating effect on the receptor. In fact the paper by Kanno et al demonstrates this effect by bathing cells in DHT alone or in DHT + YK11. Those cells that received both DHT and YK11 had less androgenic stimulation than with DHT alone. This is important since, in the presence of stronger androgens, YK11 will actually reduce androgen receptor stimulation. In the case of the prostate or hair follicle, this can be a good thing. In skeletal muscle, this will not be a good thing.
Since there have been no published results of the effects of YK11 in animals or humans, it is anyone's guess what effects it will have. We do not even know if this molecule is orally bioavailable but since it is steroidal, there is a good chance that it may not be. Furthermore, since it is a partial agonist, there is no reason to believe that it would be anabolic in people with normal levels of testosterone. Finally, we have no idea if this molecule is even remotely safe. Does it elevate liver enzymes, is it genotoxic or carcinogenic? New drugs go through a rigorous toxicological screening to ensure they are safe. To my knowledge, at least judging from the literature, none of this has been done with YK11. There are just too many unknowns with this compound to even consider using it.
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