GTx-024雄激素受体SARM Enobosarm肌肉消耗治疗Ostarine MK-2866
基本细节

2.Ostarine是选择性雄激素受体调节剂（SARM）和一种白色粉末。star属于化学原料。它也被称为enobosarm。 MK-2866或Ostarine是它的常用名称.Ki为3.8nM，对合成代谢器官具有组织选择性作用
它是口服生物可利用的非甾体选择性雄激素受体调节剂。因此，ostarine可用于治疗肌肉萎缩和骨质疏松症等疾病。
奥沙星雄激素受体（AR）与SARM的亲和力最高，Ki值为3.8 nM。 Ostarine浓度为10 nM作用于共转染的人类AR表达载体，荧光素酶报告载体和β-半乳糖苷酶对照载体CV-1细胞，调节AR转录活性。ivity.
Ostarine以10 mg / kg剂量单独静脉治疗，血药浓度下降缓慢，半衰期较长6小时，而其他氰基/硝基取代SARM的作用则半衰期为2.6-4.0小时。通过刺激前列腺，精囊和肛提肌肌肉生长，用明显的雄激素和合成代谢活性治疗的阉割的雄性大鼠中的Ostarine作用，更有效的替代除了氰基/硝基SARM的作用。 Ostarine回收率为前列腺重量的39.2％，精囊重量恢复78.8％，与其他男性器官比较，提高肛提肌增长141.9％。与在体内的任何非甾体AR激动剂相比，与前列腺，精囊和肛门中最高提臀作用的Ostarine雄激素和合成代谢活性相比，与作用于前列腺，精囊和肛门的睾酮丙酸酯（TP）相比，ED 50值分别为0.12,0.39和0.03提肛肌肌肉效果更好四倍。 Ostarine每天以0.03mg剂量同化组织处理，可以起到效率和选择性。
MK-2886的半衰期为24小时。每一剂量应每天服用一次。在非肌肉组织中不具有雄激素特性。
MK-2886完全无副作用。唯一的威胁是，有可能在4周内经历一些温和的自然测试周期，但周期之间的时间只有4周。
3.Function
它的Ostarine使用：
增加精益质量增益
增强力量
身体锻炼
联合愈合能力
激素合成代谢原料（即使剂量低至3毫克）
对于健美：Enobosarm（Ostarine，MK-2866，GTx-024）影响肌肉和骨骼，主要用于骨质疏松症，但也影响老年人的平卧肌无力和逆转肌肉减少症以及癌症患者的恶病质
用于切割：用于治疗动物模型中骨质疏松症和肌肉消瘦的非甾体选择性雄激素受体调节剂（SARM）。一种潜在的治疗性欲欲障碍的化合物。
对于重建：由于营养分配结果，Ostarine因重新开始发光。卡路里用于建立肌肉，有助于减肥，增强肌肉的质量和力量。建议剂量为12.5-25 mg，持续4-8周。
4.coa

GTx-024 Androgen Receptor SARM Enobosarm Muscle wasting Treatment Ostarine MK-2866
1.Basic Details

2.Ostarine is selective androgen receptor modulator(SARM) and a kind of white powder.Ostarine belongs to chemical raw material. It is also known as enobosarm. MK-2866 or Ostarine is the common used name of it.Ki of 3.8 nM, have tissue-selective effect on the anabolic organ
It is an orally bioavailable nonsteroidal selective androgen receptor modulator. Therefore, ostarine can beused for treatment of conditions such as muscle wasting and osteoporosis.
Ostarine androgen receptor (AR) binding with highest affinity of SARMs, Ki value of 3.8 nM. Ostarine concentration of 10 nM acting on the co-transfected human AR expression vectors, luciferase reporter vector and β- galactosidase control vector CV-1 cells, regulate AR transcriptional activity.tivity.ivity.
Ostarine by 10 mg / kg dose of intravenous treatment alone, a slow decline in plasma concentrations, longer half-life for 6 hours, while the role of the other cyano / nitro group substituted SARMs, the half-life is 2.6-4.0 hours. Ostarine role in castrated male rats treated with significant androgenic and anabolic activity, by stimulating the prostate, seminal vesicles, and levator ani muscle growth, more effective action to replace other than the cyano / nitro group SARMs. Ostarine recover 39.2% by weight of the prostate, seminal vesicle weight recovery 78.8%, and compared with other male sexual organs, stimulate the levator ani muscle growth to a greater extent, up 141.9 percent. Compared with any non-steroidal AR agonist in vivo, Ostarine androgenic and anabolic activity of the highest levator role in the prostate, seminal vesicles, and anus, ED50 values were 0.12, 0.39 and 0.03, compared with Testosterone Propionate (TP) acting on the levator ani muscle effect more four times. Ostarine treated daily at 0.03 mg dose assimilation tissue, can play efficiency and selectivity.
MK-2886 has a half-life of 24 hours. Each dose should be taken ONCE per day.It doesn't have androgenic properties in non-muscle tissue.
MK-2886 is fully side effect free. The only threat is that it's possible to experience some mild natural test shut down in cycles over 4 weeks, but the time between cycles are only 4 weeks.
3.Function
Its Ostarine use:
Increasing lean mass gains
Enhancement for strength
Bodybuiling exercise
Joint healing abilities
Hormone Anabolic raw material (even at doses as low as 3 mg)
For bodybuilding:Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients
For cutting:Nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder.
For Recomping:Ostarine shines in recomping due to its nutrient portioning results. Calorie is used to build muscle which helps in weight loss and enhancing muscle mass and strength. Suggested dosing is 12.5-25 mg for 4-8 weeks.
4.COA