吡非尼酮
cas：53179-13-8
其他名称：5-甲基-N-苯基-2-1H-吡啶酮
外观：白色结晶粉末
熔点：102--109℃
溶解性：DMSO：10mg / mL，可溶
干燥失重 <1.0%1.0%
已知单一杂质 <1.0%1.0%
未知的单一杂质 <0.5%0.5%
总杂质 <2.0%2.0%
测定（干燥）99％min
mw：185.22
mf：c12h11no
应用：
吡非尼酮是用于治疗特发性肺纤维化的抗炎药物。抗纤维蛋白酶，
有效的肺和肺纤维化模型。抑制胶原蛋白的生成和成纤维细胞
增殖。调节体内口服给药后的细胞因子水平。强力清道夫的自由
自由基和脂质过氧化抑制剂。吡非尼酮可抑制胶原蛋白的产生和成纤维细胞
增殖。在各种动物模型中显示出抗纤维化和抗炎特性
肺纤维化和临床试验。
体外，吡非尼酮可以抑制子宫肌瘤细胞和平滑肌瘤细胞的增殖。
吡非尼酮可以抑制TGF-β-1诱导成纤维细胞胶原的形成。抑制PDGF，
FGF和TGF-β-1诱导成纤维细胞增殖。在仓鼠模型中，吡非尼酮，口服，可预防和治疗博莱霉素诱导的肺纤维化。吡非尼酮可以
预防化学诱导的大鼠硬化性腹膜炎，也可以进行瘢痕疙瘩移植
治疗裸鼠。吡非尼酮0.01 1 mg / ml可以抑制基质和剂量依赖性方式血清刺激子宫肌瘤和平滑肌瘤细胞DNA合成，该化合物无细胞毒
效果，对胶原mRNA水平也没有影响。吡非尼酮在仓鼠肺纤维化模型中可以减少胶原蛋白I mRNA水平升高之前的疾病，降低肺水平
羟脯氨酸和丙二醛和肺保存氨酰羟化酶活性。
我们的任务：
为客户提供优质的个人服务，发展长期的关系，开会
他们在预算和时间框架内的具体需求。确保合规性达到最大化
通过优化的验证和控制流程，客户的核心竞争力和产品质量。
我们的愿景：
通过我们的顾问，促进主动纪律，灵活性和团队合作。确保我们所有人
服务符合当地，联邦和地区的客户要求，政策和程序
国际机构规定。
SARMS我们提供：

类固醇激素粉
半成品注射/口服类固醇：
测试prop ----------- 100mg / ml 200mg / ml
试验结果----------- 250mg / ml 300mg / ml 400mg / ml 500mg / ml 600mg / ml
测试cyp ------------ 200mg / ml 250mg / ml 300mg / ml
测试Sustanon ------- 200mg / ml 250mg / ml 300mg / ml 400mg / ml
Deca ---------------- 200mg / ml 250mg / ml
设备----------- 200mg / ml 300mg / ml
Tren ace ------------ 100mg / ml 200mg / ml
Tren enan ----------- 100mg / ml 200mg / ml
DIANABOL ------------ 50毫克/毫升
Winstrol ------------ 50毫克/毫升
Masteron ------------ 100mg / ml 150mg / ml
Primobolone --------- 100毫克/毫升
Supertest ----------- 450毫克/毫升
Anomass ------------ 400mg / ml
Ripex --------------- 225mg / ml的
Tritren ------------- 180毫克/毫升
三试------------ 300mg / ml
三癸------------ 300mg / ml
试验混合---------- 450mg / ml 500mg / ml
Nandro试验--------- 225mg / ml
质量----------------为500mg / ml的
切库----------- 400mg / ml
Tren测试----------- 225mg / ml
Nandro测试站--------- 450mg / ml
Equi Test ----------------- 450mg / ml
Rip Cut ------------------- 175mg / ml
泰伦测试站----------- 450mg / ml
我们的优势
1.我们有出口类固醇的经验，如你所知，欧盟非常重视他们，你必须找到一个有经验的合作伙伴，向你保证;
2.质量：我公司是中国制药领域的专业厂房，我们有稳定的客户，出口德国，西班牙，英国，美国，澳大利亚，中东等国家。我们可以为我们公司提供良好的参考。至于产品的质量，我们确信他们能够很好地满足你的需求。
3.包装：专业包装专业材料
4.交货：我们有库存产品，我们将在您的采购订单到达时尽快交货。同时我们会给您跟踪号码，以便让您知道产品的确切位置。我们会跟踪产品，直到他们到达你;我们为您选择最好的快递服务，并在5-7个工作日内交货。
5.服务：最佳服务，售后服务和咨询

Pirfenidone
CAS: 53179-13-8
Other Name: 5-Methyl-N-phenyl-2-1H-pyridone
Appearance: White crystal powder
Melting point: 102--109
Solubility: DMSO: 10 mg/mL, soluble
Loss on drying <1.0%1.0%
Known single impurity <1.0%1.0%
Unknown single impurity <0.5%0.5%
Total impurity <2.0%2.0%
Assay(as dried) 99%min
MW: 185.22
MF : C12H11NO
Application:
Pirfenidone is an anti-inflammatory drug used to treat idiopathic pulmonary fibrosis.Antifibrotic agent,
effective in models of pulmonary and lung fibrosis. Inhibits collagen production and fibroblast
proliferation. Regulates cytokine levels following oral administration in vivo. Potent scavenger of free
radicals and inhibitor of lipid peroxidation.Pirfenidone inhibits collagen production and fibroblast
proliferation. It has shown antifibrotic and anti-inflammatory properties in variety of animal models of
pulmonary fibrosis, and in clinical trials.
In vitro, pirfenidone can inhibit the uterine flesh tumour cells and leiomyoma cells proliferation.
Pirfenidone can inhibit the TGF - beta - 1 inducing fibroblast collagen formation. Inhibition of PDGF,
FGF and TGF - beta - 1 inducing fibroblast proliferation. In hamster model, pirfenidone, taken by mouth, that can the prevention and treatment of pulmonary fibrosis induced by bleomycin. Pirfenidone can
prevent the sclerosing peritonitis in rats induced by chemical, can also be keloid grafting for the
treatment of nude mice. Pirfenidone 0.01 1 mg/ml can suppress the matrix and dose dependent manner serum stimulate uterine fibroids and leiomyoma cell DNA synthesis, the compound has no cytotoxic
effect, has no effect on collagen mRNA level also. Pirfenidone in hamster pulmonary fibrosis model can reduce the disease before the collagen I mRNA level enhancement, reduce the level of the lung
hydroxyproline and malondialadehyde and lung preserved ammonia acyl hydroxylase activity.
Our mission:
Provide our customer with an excellent personal service which develops long-term relationship, meeting
their specific needs within budget and time frame. Ensure regulatory compliance are maximize on
clients core competencies and product quality through optimized validated and controlled processes.
Our vision:
Promote initiative discipline, flexibility and team work through our consultants.Ensure that all of our
services comply with customer requirements, policies, and procedures with local, federal and
international agencies regulations.
SARMS We offer:

Steroid Hormone Powder:
Semi-finished Injectable / Oral steroids:
Test prop-----------100mg/ml 200mg/ml
Test enan-----------250mg/ml 300mg/ml 400mg/ml 500mg/ml 600mg/ml
Test cyp------------200mg/ml 250mg/ml 300mg/ml
Test Sustanon-------200mg/ml 250mg/ml 300mg/ml 400mg/ml
Deca----------------200mg/ml 250mg/ml
Equipoise-----------200mg/ml 300mg/ml
Tren ace------------100mg/ml 200mg/ml
Tren enan-----------100mg/ml 200mg/ml
Dianabol------------50mg/ml
Winstrol------------50mg/ml
Masteron------------100mg/ml 150mg/ml
Primobolone---------100mg/ml
Supertest-----------450mg/ml
Anomass ------------400mg/ml
Ripex---------------225mg/ml
Tritren-------------180mg/ml
Tri Test------------300mg/ml
Tri Deca------------300mg/ml
Test Blend----------450mg/ml 500mg/ml
Nandro Test---------225mg/ml
Mass----------------500mg/ml
Cut Depot-----------400mg/ml
Tren Test-----------225mg/ml
Nandro Test Depot---------450mg/ml
Equi Test-----------------450mg/ml
Rip Cut-------------------175mg/ml
Tren Test Depot-----------450mg/ml
Our advantage
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation