Nobiletin 是从柑橘皮剥离的柑橘类黄酮，类似于tangeretin结构。它具有典型的类黄酮结构，并含有6个甲氧基。它是一种具有挽救球囊切除术诱导的记忆障碍的活性的O-甲基化黄酮。纯的甘草素具有无色针状的外观，并具有苦味。

大多数研究的川studied苷的性质是其抗炎和抗癌活性。 Nobiletin也有助于降低胆固醇水平，一些研究表明它可能 改善受损记忆 和 治疗痤疮.

Nobiletin直接作为抗氧化剂，但也干扰生物炎症过程。它通过阻断NF-kappaB与DNA的结合来抑制参与炎症的基因的表达。一项研究表明，去甲肾上腺素减少哮喘大鼠的气道炎症。用去甲肾上腺素处理皮肤细胞也减少了由紫外线辐射引起的炎症。

Nobiletin通过其抗增殖作用而没有对正常细胞的毒性。它对包括肝，胃，前列腺和结肠的癌症有效。
Nobiletin抑制巨噬细胞泡沫细胞，装载有脂质的巨噬细胞的形成，其在动脉壁上积累。并且研究表明它适用于治疗记忆障碍。

基本数据
植物来源：枸杞，枸杞
同义词：3'，4'，5,6,7,8-六甲氧基黄酮
规格可用：45％，90％HPLC
包装：25kg /桶;克/小袋
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Nobiletin产品链接：http://www.chinwonbio.com/index.php/product/index/g/e/id/4.html

Nobiletin is a citrus flavonoids isolated from citrus peels, similar to tangeretin structure. It has the typical flavonoid structure and contains 6 methoxyl groups. It is an O-methylated flavone that has the activity to rescue bulbectomy-induced memory impairment.Pure nobiletin has the appearance of colorless needles and has a bitter taste.

Most studied properties of nobiletin are its anti-inflammatory and anti-cancer activities. Nobiletin also helps to lower cholesterol levels and some studies indicate that it may improve impaired memory and treat acne.

Nobiletin acts directly as an antioxidant but also interferes with biological inflammatory processes. It inhibits the expression of genes involved in inflammation by blocking the binding of NF-kappaB with DNA. One study showed that nobiletin reduced airway inflammation of asthmatic rats. Treatment of skin cells with nobiletin also reduced inflammation caused by ultraviolet-B.radiation.

Nobiletin acts by its antiproliferation effect without being toxic to normal cells. It is effective on the cancers including liver, stomach, prostate and colon.
Nobiletin inhibits the formation of macrophage foam cells, macrophages loaded wit lipids, which build up on artery walls. and also study shows that it works well for treating memory impairments.

Basic Data
Botanical Source: Citrus aurantium, Citrus Depressa Hayata
Synonyms: 3',4',5,6,7,8-hexamethoxyflavone
Specifications available: 45%,90% HPLC
Package: 25kg/drum; grams/sachet
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Nobiletin product link: http://www.chinwonbio.com/index.php/product/index/g/e/id/4.html