雌酮
雌三烯
产品名称：1,3,5（10） - 地斯林-3-醇-17-酮
同义词：（8R，13S）-3-羟基-13-甲基-6,7,8,9,11,12,13,14,15,16-十氢 - 环戊二烯并苯-1-酮; 1， 3,5（10）-Oestratrien -3-醇-17-酮; 1,3,5- Oestratrien -3-醇-17-酮; 3-羟基-1,3,5-（10）-oestratrien-17 - 酮; 3-羟基-1,3,5（10）-oestratrien -17-酮; 3-羟基-17- ketoestra -1,3,5-三烯; 3-羟基-17- ketoestra-1， 3,5-三烯; 3-羟基-17-酮 - 雌-1,3,5-三烯
cas：53-16-7
mf：c18h22o2
mw：270.37
einecs：200-164-5
化学性质结晶固体
用法17β-雌二醇二醇的代谢物。adiol.
使用雌激素
用法17-雌二醇的代谢物
Estrone说明：
雌激素是三种天然雌激素之一，其他雌二醇和雌三醇。雌激素由雌二醇通过芳香酶系统在卵巢和胎盘中合成，并由雌二醇通过17-羟基类固醇脱氢酶在肝脏中合成。绝经前妇女的雌激素浓度根据月经周期波动，成为绝经后妇女中最主要的雌激素。雌酮与雌激素受体α和β的结合亲和力相对于雌二醇雌二醇约为60％和37％。o estradiol.
Estrone应用：
艾斯特龙被认为是人类女性的致癌物，也会导致乳房触痛或疼痛，恶心，头痛，高血压和腿部痉挛。在男性中，已知雌酮引起厌食，恶心，呕吐和勃起功能障碍。 Estrone与健康和疾病状态相关，因为它转化为硫酸雌酮，这是一种长寿命的衍生物。硫酸埃斯特龙作为可以根据需要转化为更活泼的雌二醇的储库。绝经后女性主要是雌激素。
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Estrone
Estratrien
Product Name: 1,3,5(10)-Estratrien-3-ol-17-one
Synonyms: (8R,13S)-3-Hydroxy-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydro-cyclopenta[a]phenanthren-17-one;1,3,5(10)-Oestratrien-3-ol-17-one;1,3,5-Oestratrien-3-ol-17-one;3-Hydroxy-1,3,5-(10)-oestratrien-17-one;3-Hydroxy-1,3,5(10)-oestratrien-17-one;3-hydroxy-17-keto-estra-1,3,5-triene;3-Hydroxy-17-ketoestra-1,3,5-triene;3-hydroxy-17-keto-oestra-1,3,5-triene
CAS: 53-16-7
MF: C18H22O2
MW: 270.37
EINECS: 200-164-5
Chemical Properties Crystalline Solid
Usage A metabolite of 17β-Estradiol.adiol.adiol.
Usage estrogen
Usage A metabolite of 17-Estradiol
Estrone Description:
Estrone is one of the three naturally occurring estrogens, the others being estradiol and estriol.Estrone is synthesized from androstenedione by the aromatase enzyme system in the ovaries and placenta, and is also synthesized from estradiol by 17-hydroxy steroid dehydrogenase in the liver.Serum concentrations of estrone in premenopausal women fluctuate according to the menstral cycle and becomes the most predominant estrogen in postmenopausal women. The binding affinities of estrone to the estrogen receptors α and β are approximately 60% and 37% relative to estradiol.o estradiol.o estradiol.
Estrone Applications:
Estrone is known to be a carcinogen for human females as well as cause breast tenderness or pain, nausea, headache, hypertension, and leg cramps.In men, estrone has been known to cause anorexia, nausea, vomiting, and erectile disfunction. Estrone is relevant to health and disease states because of its conversion to estrone sulfate, a long-lived derivative. Estrone sulfate acts as a reservoir that can be converted as needed to the more active estradiol. It is the predominant estrogen in postmenopausal women.
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