Local Anesthetic Drug Reduce Pain Dentistry CAS 51-05-8 Procaine HCl

Local Anesthetic Drug Reduce Pain Dentistry CAS 51-05-8 Procaine HCl

局部麻醉药减少疼痛牙科CAS 51-05-8 Procaine HCl

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型号。 cas 51-05-8
定制 非定制
适合 成人
纯度 >99%
出场 白色粉末
包装细节 箔包与谨慎的包装
运输包装 1kg无菌铝箔袋或谨慎
起源 中国
粉末
证明 gmp,hse,iso 9001,usp,bp
固体
产品名称 盐酸普鲁卡因
用法 身体肌肉增益
商标 whsm
规范 gmp,sgs,iso,kosher
HS编码 2937290090
99%症状溶解,抗炎粉减轻肌内注射疼痛,用于龋齿盐酸普鲁卡因CAS 51-05-8
1.详细说明:
产品名称 盐酸普鲁卡因
别号 盐酸普鲁卡因aminocaine; anadolor
CAS 51-05-8
EINECS 200-077-2
化验 99.0%
出现 白色结晶粉末
分子式 c13h21cln2o2
分子量 272.77
年级 医药级
存储 阴影,密闭保存
品牌 njbn类固醇

2.产品说明:
普鲁卡因是氨基酯基团的局部麻醉药物。它主要用于减少肌内注射青霉素的疼痛,并且也用于牙科。由于商业名称Novocain无处不在。它主要作为钠通道阻滞剂。今天由于其交感神经,抗炎,灌注增强和情绪增强作用,在一些国家被用于治疗。
普鲁卡因首先在1905年,阿米卡因不久之后合成。它是由德国化学家阿尔弗雷德·埃因霍恩(Alfred Einhorn)创造的,他将化学品的商品名称从拉丁语nov-(意思是新的)和-caine,作为用作麻醉剂的生物碱的共同终点。外科医生海因里希·布劳恩(Heinrich Braun)将其引入医疗用途。然而,牙医认为它非常有用。
3.适用范围:
像其他局部麻醉剂(如甲哌卡因和丙胺卡因)一样,普鲁卡因是一种血管扩张剂,因此经常与肾上腺素共同施用以用于血管收缩。血管收缩有助于减少出血,增加麻醉的持续时间和质量,防止药物大量体内循环,并且总体减少麻醉剂的需要量。
普鲁卡因是一种酯麻醉剂,通过酶水解成原氨基苯甲酸(PABA),通过酶假胆碱酯酶在血浆中代谢,然后将其从肾脏排泄到尿液中。
普罗卡因是阿拉·阿斯兰(罗马尼亚)在争议性制备Gerovital H3中的主要成分,该倡导者主张补救老化的许多影响。主流医学观点是,这些说法在20世纪60年代被认真研究和抹黑。
推荐1%普鲁卡因注射液用于治疗与静脉穿刺相关的外渗并发症(以及潮热,ASA,类固醇,抗生素)。同样推荐治疗无意的动脉内注射(10ml 1%普鲁卡因),因为它有助于缓解疼痛和血管痉挛。
4. coa:
产品名称 盐酸普鲁卡因
出现 白色结晶性粉末
测定(C13H2ON2O2·HCl)点; HCl)dot;HCl) 99.0%〜101.0% 99.5%
熔点 153〜158ºCordm; C ^ordm;C 156.5〜157.0ºCordm; C ^ordm;C
重金属 ≤20ppm0ppm0ppm <5ppm5ppm
酸度 ≤0.02NNaOH 0.5ml.5ml.5ml 0.3毫升
色谱纯度 次要斑点≤0.5%,总和≤1.0%,1.0%le;1.0% 符合
干燥失重 ≤1.0%1.0%1.0% 0.06%
炽灼残渣 ≤0.15%0.15%.15% 0.03%
细菌内毒素 ≤0.6EU/ MGU /毫克U/mg <0.6EU/mgU/mg

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Model NO. CAS 51-05-8
Customized Non-Customized
Suitable for Adult
Purity >99%
Appearances White Powder
Packaging Detail Foil Bag with Discreet Package
Transport Package 1kg Sterile Aluminum Foil Bag or Discreet
Origin China
Powder Yes
Certification GMP, HSE, ISO 9001, USP, BP
State Solid
Product Name Procaine HCl
Usage Body Muscle Gain
Trademark whsm
Specification GMP, SGS, ISO, KOSHER
HS Code 2937290090
99% Sympatholytic, Anti-inflammatory Powder to Reduce the Pain of Intramuscular Injection and Used in Dentistry Procaine Hydrochloride CAS 51-05-8
1. Quick Detail:
Product Name Procaine HCl
Alias Procaine hydrochloride; aminocaine;anadolor
CAS 51-05-8
Einecs 200-077-2
Assay 99.0%
Appearance White Crystalline Powder
Molecular Formula C13H21ClN2O2
Molecular Weight 272.77
Grade Pharmaceutical Grade
Storage Shading, Confined Preservation
Brand Name NJBN STEROID

2. Product description:
Procaine is a local anesthetic drug of the amino ester group. It is used primarily to reduce the pain of intramuscular injection of penicillin, and it is also used in dentistry. Owing to the ubiquity of the trade name Novocain, . It acts mainly as a sodium channel blocker. Today it is used therapeutically in some countries due to its sympatholytic, anti-inflammatory, perfusion enhancing, and mood enhancing effects.
Procaine was first synthesized in 1905, shortly after amylocaine. It was created by the German chemist Alfred Einhorn who gave the chemical the trade name , from the Latin nov- (meaning new) and -caine, a common ending for alkaloids used as anesthetics. It was introduced into medical use by surgeon Heinrich Braun.Dentists, however, found it very useful.
3. Application:
Like other local anesthetics (such as mepivacaine, and prilocaine), procaine is a vasodilator, and is thus often coadministered with epinephrine for the purpose of vasoconstriction. Vasoconstriction helps to reduce bleeding, increases the duration and quality of anesthesia, prevents the drug from reaching systemic circulation in large amounts, and overall reduces the amount of anesthetic required.
Procaine, an ester anesthetic, is metabolized in the plasma by the enzyme pseudocholinesterase through hydrolysis intopara-amino benzoic acid (PABA), which is then excreted by the kidneys into the urine.
Procaine is the primary ingredient in the controversial preparation Gerovital H3 by Ana Aslan (Romania), which is claimed by its advocates to remedy many effects of aging. The mainstream medical view is that these claims were seriously studied and discredited in the 1960s.
A 1% procaine injection has been recommended for the treatment of extravasation complications associated with venipuncture (along with moist heat, ASA, steroids, antibiotics). It has likewise been recommended for treatment of inadvertent intra-arterial injections (10 ml of 1% procaine), as it helps relieve pain and vascular spasm.
4. COA :
Product name Procaine HCl
Appearance White crystalline powder
Assay (C13H20N2O2·HCl)dot;HCl)dot;HCl) 99.0% to 101.0% 99.5%
Melting point 153~158ºCordm;Cordm;C 156.5~157.0ºCordm;Cordm;C
Heavy metals ≤20ppm0ppm0ppm <5ppm5ppm
Acidity ≤0.02N NaOH 0.5ml.5ml.5ml 0.3ml
Chromatographic purity Secondary spots≤0.5%,sum≤1.0%le;1.0%le;1.0% Conforms
Loss on drying ≤1.0%1.0%1.0% 0.06%
Residue on ignition ≤0.15%.15%.15% 0.03%
Bacterial endotoxins ≤0.6EU/mgU/mgU/mg <0.6EU/mgU/mg

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