男性Melanotan II多肽激素肽粉末Melanotan 2 / Mt2

Melanotan-II
序列：Ac-Nle-环Asp-His-D-Phe-Arg-Trp-Lys'-NH 2
别名：Melanotan II，7） - 内酰胺，Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH 2;
Ac-Nle4，Asp5，D-Phe7，Lys10'alpha-MSH-（4-10）-NH2
分子式：C 50 H 69 N 15 O 9
mw：1024.180
CAS编号：121062-08-6
等级：医药级
纯度：99％
外观：白色粉末
贮存：关闭，低于2〜8℃保存
制造商：SMQ
交货时间：收到付款后18小时内
交货：ems，dhl，tnt，fedex，ups
用途：Melanotan 2在研究中显示除了促进皮肤鞣制之外，还显示出食欲抑制，脂肪分解和性欲增强作用。美拉诺坦2已被广泛研究用于防止由于其黑素生成刺激性质而对来自日光的紫外线辐射的有害影响。

描述：

Melanotan-II

美拉诺坦可以指两种单独的肽之一：Afamelanotide，最初以名称“Melanotan-1”或“Melanotan I”开发用于皮肤鞣制，目前以植入形式试验的药物作为一系列轻度感染皮肤的预防性治疗疾病和潜在的皮肤癌预防剂。
Melanotan II，一种最初作为皮肤鞣剂开发的药物，但随后被研究作为性功能障碍的潜在治疗。
美拉诺坦2（也称为美拉诺坦II）是在体内天然产生的肽激素的合成产生的变体，其刺激黑素生成，所述黑素生成是负责皮肤色素沉着的过程。这种肽激素，称为α-黑素细胞刺激激素或MSH，在发挥其作用的过程中激活某些黑皮质素受体。事实上，MSH还通过这些黑皮质素受体对脂质代谢，食欲和性欲有显着的影响。因此，除了促进皮肤鞣制之外，美拉诺坦2已经在研究中显示表现出食欲抑制剂，脂肪分解和性欲增强效应。美拉诺坦2已被广泛研究用于防止由于其黑素生成刺激性质而对来自日光的紫外线辐射的有害影响。
另外，已经将Melanotan 2和类似的合成产生的变体（称为PT-141）长期研究作为治疗性功能障碍的潜在疗法;特别是男性勃起功能障碍。

Melanotan 2研究和更多信息

美拉诺坦和美拉诺坦2都是倾向于诱导皮肤晒黑的肽激素α-黑素细胞刺激激素（α-MSH）的类似物。与Melanotan 1不同，Melanotan 2已显示具有春药属性，增加性欲的额外效果。美拉诺坦2是α-促黑素细胞激素（α-MSH）的环状七肽类似物。
还研究了美拉诺坦2对实验室小鼠的饮食和食物摄取的影响。已经证明，当在小鼠中喂食和诱导时，中心黑素皮质素（MC）已被黑色素2活化。美拉诺坦2的6天治疗显示该肽实际上减少了小鼠内脏中的体重和脂肪组织，并抑制了该生物体的热量摄入。这具有在可能的治疗的减少碳水化合物或卡路里摄入，特别是对于超重和肥胖的临床应用的影响。此外，相同的研究还表明，肥胖动物的可用氧消耗持续增加。与对照处理相比，Melanotan 2还有助于降低血清胰岛素和胆固醇水平的水平。此外，已经表明melanotan 2实际上降低了乙酰胆碱A caboxylase表达的水平，甚至通过在肥胖大鼠的肌肉中的配对喂养来防止肌肉型组织中肉碱和棕榈醇转移酶I mRNA的减少。此外，美拉诺2肽实际上增加了肌肉中的脂肪分解代谢，甚至改善了胆固醇代谢（Li等人2004）。


应用：

Melanotan-II

已经研究了α-MSH的一些合成类似物对于它们对来自太阳的紫外线（UV）辐射即Melanotan（afamelanotide）和Melanotan II（称为Melanotan 2）的表观光保护作用。Bremelanotide是α-MSH的另一种类似物到Melanotan 2，目前正在开发用于治疗性功能障碍。所有这些黑素肽具有比α-MSH显着更大的效力，但具有不同的选择性肽谱。

有各种各样的肽你可以选择。它可以帮助你失去你的重量，并获得你的肌肉。这也是一个不错的选择，请检查我们的产品列表。

Melanotan II，一种最初作为皮肤鞣剂开发的药物，但随后被研究作为性功能障碍的潜在治疗。

美拉诺坦2（也称为美拉诺坦II）是在体内天然产生的肽激素的合成产生的变体，其刺激黑素生成，所述黑素生成是负责皮肤色素沉着的过程。这种肽激素，称为α-黑素细胞刺激激素或MSH，在发挥其作用的过程中激活某些黑皮质素受体。事实上，MSH还通过这些黑皮质素受体对脂质代谢，食欲和性欲有强烈的影响。因此，除了促进皮肤鞣制之外，美拉诺坦2已经在研究中显示表现出食欲抑制剂，脂肪分解和性欲增强效应。美拉诺坦2已被广泛研究用于防止由于其黑素生成刺激性质而对来自日光的紫外线辐射的有害影响。

另外，已经将Melanotan 2和类似的合成产生的变体（称为PT-141）长期研究作为治疗性功能障碍的潜在疗法;特别是男性勃起功能障碍。


剂量和用法

像我们迄今为止讨论的每个肽，请记住肽是以白色精致粉末的形式，并应在阴凉干燥的地方的光存储。所有肽都需要用专门用于注射的抑菌水或氯化钠重构。为了有效地使用Melanotan II，你需要了解你的皮肤类型。为了保持简单，我们可以继续，将皮肤类型分为三类。

皮肤类型1：非常平整的皮肤，从不晒黑。剂量：50-60mgs或5-6vips。
皮肤类型2：皮肤平滑，灼伤，但有时晒伤。剂量：30-40mgs或3-4瓶。
皮肤类型3：中度皮肤，有时灼伤，总是晒黑。剂量：20mg或2瓶。
除此之外，如果你的色素沉着已经是自然橄榄色或更深，你需要使用更少的眼影II来满足你的鞣制需求。棕褐色的结果加上暴露在阳光和紫外线下应该在整个夏天或整个季节持续一个用户。

每日剂量根据您的需要而有所不同：

对于勃起功能障碍（ED）：平均剂量为约0.025mgs / kg（1kg = 2.2lbs）
对于晒黑（皮肤色素沉着）：平均剂量为0.025-0.030mgs / kg（1kg = 2.2lbs）
服用过多的M2会使你略带淡黄色，所以你需要慢慢地开始低剂量，并向上移动。

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其他肽：

Male Melanotan II Peptides Hormone Peptide Powder Melanotan 2 / Mt2

Melanotan-II
Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Alias : Melanotan II, 7)-lactam, Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2;
Ac-[Nle4,Asp5,D-Phe7,Lys10]alpha-MSH-(4-10)-NH2
Molecular formula: C50H69N15O9
MW : 1024.180
CAS number: 121062-08-6
Grade : Pharmaceutical Grade
Purity : 99%
Appearance : White Powder
Storage: Closed, below 2 ~ 8oC preservation
Manufacturer :SMQ
Delivery time : within 18 hours upon receipt of payment
Delivery: EMS, DHL, TNT, FedEx, UPS
Usage : Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Description:

Melanotan-II

Melanotan may refer to one of two separate peptides : Afamelanotide, originally developed under the names 'Melanotan-1' or 'Melanotan I' for skin tanning, a drug currently in trials in implant form as a prophylactic treatment for a series of light affected skin disorders and potential skin cancer preventative agent.
Melanotan II, a drug originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction.
Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.
Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

Melanotan 2 Studies and Further Information

Melanotan and Melanotan 2 are both analogs of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that tend to induce skin tanning. Unlike Melanotan 1, Melanotan 2 has been shown to have aphrodisiac properties, the additional effect of increasing libido. Melanotan 2 is a cyclic heptapeptide analog of the alpha-melanocyte stimulating hormone (a-MSH).
The effects of Melanotan 2 on the diet and food intake of the laboratory mice have also been investigated. It has been demonstrated that the central melanocortin (MC) has been activated by melanotan 2 when fed and induced in the mice. The six-day treatment of Melanotan 2 has shown that the peptide actually reduced the body weight and the adipose tissue in the viscera of the mice and suppressed the caloric intake of the organism. This has implications in clinical applications of the possible treatment to reduce carbohydrate or calorie intake especially for the overweight and the obese. Furthermore, the same study has also demonstrated that there was a sustained increase in the available oxygen consumption in obese animals. Melanotan 2 also helped reduced the level of serum insulin and the cholesterol levels when compared with the control treatments. Furthermore, it has been suggested that melanotan 2 actually lowers the level of acetylcholine A caboxylase expression and even prevented the reduction of carnitine and palmitoltransferase I mRNA in muscle-type tissues by pair-feeding in the muscles of the obese rats. Moreover, the Melanotan 2 peptide actually increased the fat catabolism in the muscles and even improved the cholesterol metabolism (Li et al. 2004).


Application:

Melanotan-II

A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.

There are all kinds of peptides you can choose .It can help you loss your weight and gain your muscles . This is also a good choice for you ,please check our product lists.

Melanotan II, a drug originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction.

Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin. This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.


Dosages and Usage

Like every peptide we have discussed thus far, please remember that peptides come in the form of a white delicate powder and should be stored out of light in a cool dry place. All peptides need to be reconstituted with bacteriostatic water or sodium chloride specifically used for injections. In order to use Melanotan II effectively, you need to understand your skin type. To keep things simple, we can go ahead and break skin types into three categories.

Skin Type 1: Very fair skin, never tans. Dosages: 50-60mgs or 5-6vials.
Skin Type 2: Fair skin, burns but sometimes tans. Dosages: 30-40mgs or 3-4 vials.
Skin Type 3: Medium skin, sometimes burns and always tans. Dosages: 20mgs or 2 vials.
Beyond that, if your pigmentation is already naturally olive or darker, you will need to use less Meanotan II for your tanning needs. The tan results coupled with exposure to sunlight and UV rays should last a user all summer or through a season.

Daily Dosages vary depending on your needs:

For Erectile Dysfunction (ED): average dose is around 0.025 mgs/kg (1kg = 2.2 lbs)
For Tanning (skin pigmentation): average dose is 0.025-0.030 mgs/kg (1kg = 2.2 lbs)
Taking too much M2 can make you somewhat yellowish, so you need to start slowly with lower doses and move your way up.

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