MT2药物原料注射多肽Melanotan-II

基本信息 ：

Melanotan-II
序列：Ac-Nle-环（Asp-His-D-Phe-Arg-Trp-Lys）-NH 2
别名：Melanotan II，7） - 内酰胺，Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH 2;
Ac-（Nle4，Asp5，D-Phe7，Lys10）α-MSH-（4-10）-NH2
分子式：C 50 H 69 N 15 O 9
mW：1024.180
纯度：99％
cas：121062-08-6
Pub.Chem：92432
MeSH：melanotan-II
Melanotan 2结构：Ac-cyclo（Nle4，Asp5，D-Phe7，Lys10）α-MSH4-10-NH2
外观：冻干粉，白粉
储存：关闭，低于2〜8ºC保存
用途：Melanotan 2在研究中显示除了促进皮肤晒黑外，还显示出食欲抑制，脂肪分解和性欲增强效应。美拉诺坦2已被广泛研究用于防止由于其黑素生成刺激性质而对来自日光的紫外线辐射的有害影响。

产品介绍：

美拉诺坦2（也称为美拉诺坦II）是在体内天然产生的肽激素的合成产生的变体，其刺激黑素生成，所述黑素生成是负责皮肤色素沉着的过程。美拉诺坦II是最初作为皮肤鞣剂开发的药物，但随后被调查作为性功能障碍的潜在治疗。该肽激素，称为α-黑素细胞刺激激素或MSH，在发挥其作用的过程中活化某些黑皮质素受体。事实上，MSH还通过这些黑皮质素受体对脂质代谢，食欲和性欲有强烈的影响。因此，除了促进皮肤鞣制之外，美拉诺坦2已经在研究中显示表现出食欲抑制剂，脂肪分解和性欲增强效应。美拉诺坦2已被广泛研究用于防止由于其黑素生成刺激性质而对来自日光的紫外线辐射的有害影响。另外，已经将Melanotan 2和类似的合成产生的变体（称为PT-141）治疗性功能障碍的潜在治疗;特别是男性勃起功能障碍。

使用：

已经研究了α-MSH的一些合成类似物对于它们对来自太阳的紫外线（UV）辐射即Melanotan（afamelanotide）和Melanotan II（称为Melanotan 2）的表观光保护作用。Bremelanotide是α-MSH的另一种类似物到Melanotan 2，目前正在开发用于治疗性功能障碍。所有这些黑素肽具有比α-MSH显着更大的效力，但具有不同的选择性肽谱。

产品规格：

coa：



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产品列表：

MT2 Pharmaceutical Raw Materials Injectable Polypeptide Melanotan-II

Basic Info :

Melanotan-II
Sequence: Ac-Nle-cyclo(Asp-His-D-Phe-Arg-Trp-Lys)-NH2
Alias : Melanotan II, 7)-lactam, Ac-Nle-Asp-His-D-Phe-Arg-Trp-Lys-NH2;
Ac-(Nle4,Asp5,D-Phe7,Lys10)alpha-MSH-(4-10)-NH2
Molecular formula: C50H69N15O9
MW : 1024.180
Purity : 99%
CAS: 121062-08-6
PubChem: 92432
MeSH: melanotan-II
Melanotan 2 Structural Name: Ac-cyclo(Nle4, Asp5, D-Phe7, Lys10)α-MSH4-10-NH2
Appearance : Freeze dry powder,White Powder
Storage: Closed, below 2 ~ 8ºC preservation
Usage : Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.

Product introduction:

Melanotan 2 (also referred to as Melanotan II) is a synthetically produced variant of a peptide hormone naturally produced in the body that stimulates melanogenesis, a process responsible for pigmentation of the skin.Melanotan II, a drug originally developed as a skin tanning agent, but subsequently investigated as a potential treatment for sexual dysfunction.This peptide hormone, called alpha-Melanocyte stimulating hormone or MSH, activates certain melanocortin receptors in the process of exerting its effects. Indeed, MSH also exerts potent influence over lipid metabolism, appetite, and sexual libido via these melanocortin receptors. As a result, Melanotan 2 has been shown in studies to exhibit appetite suppressant, lipolytic, and libido-enhancing effects in addition to promoting skin tanning. Melanotan 2 has been researched extensively for use in protecting against the harmful effects of ultraviolet radiation from sunlight due to its melanogenesis-stimulating properties.Additionally, Melanotan 2 and a similar synthetically produced variant, known as PT-141, have been studied at length as a potential remedy for the treatment of sexual dysfunction; specifically, male erectile dysfunction.

Utilization:

A few synthetic analogues of α-MSH have been investigated for their apparent photoprotective effects against ultraviolet (UV) radiation from the sun, namely Melanotan (afamelanotide) and Melanotan II, referred to as Melanotan 2. Bremelanotide, another analogue of α-MSH similar to Melanotan 2, is currently under development for the treatment of sexual dysfunction. All of these melanotan peptides have significantly greater potencies than α-MSH, but with distinctive selectivity peptide profiles.

Specifications :

COA:



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