抗菌防腐剂BA苄醇类固醇溶液

抗菌剂
苄醇用作静脉注射药物，化妆品和局部药物中低浓度的抑菌防腐剂.BA是防止类固醇溶液灭菌的防腐剂。苄醇（BA）：一种相当有效的溶剂，其主要作用是保持目标一种溶液抑菌。低至0.9％的存在足以防止溶液中几乎所有的微生物生长。
苄醇通常是主要溶剂，有时是类固醇给定配方中唯一的溶剂。其主要功能是作为灭菌剂。然而，由于其偿付能力，它通常用于将激素保持在与油或其他车辆的溶液中。它也是最薄的（最适合降低粘度）之一。
它在类固醇中的应用是保持暂停数月甚至数年，而不会降低无菌性。酒精是一种抗菌消毒剂，并被广泛应用于许多行业。如上所述，苄醇确保当以正确浓度使用时，类固醇维持其无菌性。
增加溶解度
苄醇（BA）用于提高酯化物质的脂溶性，并防止油中的细菌生长。
酯越短，使化合物溶解所需的BA越多。需要更多的BA来溶解生粉以制备高浓度产品
副作用
然而，如果使用太多，注射类固醇就会很痛，并会引起后注射酸痛。这种溶剂的主要缺点是，如果浓度超过10％，它倾向于进行疼痛的注射。 （对于任何低分子量酒精都是如此）。对于大多数人来说，少于这一点往往是无痛的。
不幸的是，它也可能导致细胞的破坏和显着的局部疼痛和炎症。这种不适的特征是疼痛，红肿肿胀面积相当快。

Antibacterial Preservative BA Benzyl Alcohol for Steroid Solutions

Antibacterial Agent
Benzyl alcohol is used as a bacteriostatic preservative at low concentration in intravenous medications, cosmetics and topical drugs.BA is the antiseptic which keeps the steroid solution sterile.Benzyl Alcohol (BA):A fairly potent solvent, whose main function for our purposes is keeping a solution bacteriostatic. It's presence as low as 0.9% is enough to prevent practically all microbial growth in solution.
Benzyl Alcohol is often the primary solvent and sometime the only solvent in a steroid given formula. Its primary function is as a sterilizing agent. However, due to its solvency power it is often used to keep hormones in solution with oil or other vehicles. It is also one of the thinnest (that is best for viscosity reduction).
Its use in Steroids is to preserve the suspension for months, even years, without any reduction in sterility. Alcohol is an antibacterial disinfectant and is used as such in many industries. As aforementioned Benzyl Alcohol ensures the Steroid maintains its sterility when used in the right concentration.
Increase Solubility
Benzyl Alcohol (BA) is used to increase the lipid solubility of esterfied compounds and to prevent bacteria growth in the oil.
The shorter the ester, the more BA is needed to get the compound to dissolve.More BA is required to dissolve the raw powder to make high concentration products
Side Effect
However, if too much is used the Steroid will be painful to inject and will cause post injection soreness.The major drawback to this solvent is that it tends to make for painful injections if the concentration goes above 10%. (This is true for any low molecular weight alcohol). Less than this tends to be painless for most people.
Unfortunately, it can also cause the destruction of cells and significant localised pain and inflammation. The discomfort is characterised by fairly rapid onset of a painful, red, swollen area.