产品名称： 西多福韦
也名：pmpc; gs-504;维斯特（s）-hpmpc
测定：99％
cas no .: 113852-37-2
用途：抗病毒

描述：
西多福韦是用于治疗AIDS患者的巨细胞病毒（CMV）视网膜炎的可注射抗病毒药物。它通过选择性抑制病毒DNA聚合酶并因此防止病毒复制和转录来抑制CMV复制。它是无环核苷膦酸盐，因此不依赖于病毒酶的磷酸化，与例如阿昔洛韦相反。

功能：
西多福韦在新诊断的患者以及先前治疗过的其他治疗失败的患者中显示出延迟CMV视网膜炎损伤的进展的统计学显着的效果。
西多福韦也显示了治疗抗阿昔洛韦的疱疹的功效
西多福韦也已被研究作为进行性多灶性脑白质病的治疗。
西多福韦在移植患者亚组中显示出抗BK病毒活性。
西多福韦正在作为对由HPV引起的乳头状瘤病的补充性病灶内治疗进行研究

Product Name: Cidofovir
Also Name: PMPC; GS-504; Vistide; (S)-HPMPC
Assay: 99%
CAS No.: 113852-37-2
Usages: Anti-viral

Descriptions:
Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is an acyclic nucleoside phosphonate, and is therefore independent of phosphorylation by viral enzymes, in contrast to, for instance, acyclovir.

Functions:
Cidofovir demonstrated a statistically significant effect in delaying the progression of CMV retinitis lesions in newly diagnosed patients, as well as in previously treated patients who had failed other therapies.
Cidofovir has also shown efficacy in the treatment of acyclovir resistant herpes
Cidofovir has also been investigated as a treatment for progressive multifocal leukoencephalopathy.
Cidofovir shows anti-BK virus activity in a subgroup of transplant patients.
Cidofovir is being investigated as a complementary intralesional therapy against papillomatosis caused by HPV