GTx-024 Androgen Receptor SARM Enobosarm Muscle wasting Treatment Ostarine MK-2866
1.Basic Details

2.Ostarine is selective androgen receptor modulator(SARM) and a kind of white powder.Ostarine belongs to chemical raw material. It is also known as enobosarm. MK-2866 or Ostarine is the common used name of it.Ki of 3.8 nM, have tissue-selective effect on the anabolic organ
It is an orally bioavailable nonsteroidal selective androgen receptor modulator. Therefore, ostarine can beused for treatment of conditions such as muscle wasting and osteoporosis.
Ostarine androgen receptor (AR) binding with highest affinity of SARMs, Ki value of 3.8 nM. Ostarine concentration of 10 nM acting on the co-transfected human AR expression vectors, luciferase reporter vector and β- galactosidase control vector CV-1 cells, regulate AR transcriptional activity.tivity.ivity.
Ostarine by 10 mg / kg dose of intravenous treatment alone, a slow decline in plasma concentrations, longer half-life for 6 hours, while the role of the other cyano / nitro group substituted SARMs, the half-life is 2.6-4.0 hours. Ostarine role in castrated male rats treated with significant androgenic and anabolic activity, by stimulating the prostate, seminal vesicles, and levator ani muscle growth, more effective action to replace other than the cyano / nitro group SARMs. Ostarine recover 39.2% by weight of the prostate, seminal vesicle weight recovery 78.8%, and compared with other male sexual organs, stimulate the levator ani muscle growth to a greater extent, up 141.9 percent. Compared with any non-steroidal AR agonist in vivo, Ostarine androgenic and anabolic activity of the highest levator role in the prostate, seminal vesicles, and anus, ED50 values were 0.12, 0.39 and 0.03, compared with Testosterone Propionate (TP) acting on the levator ani muscle effect more four times. Ostarine treated daily at 0.03 mg dose assimilation tissue, can play efficiency and selectivity.
MK-2886 has a half-life of 24 hours. Each dose should be taken ONCE per day.It doesn't have androgenic properties in non-muscle tissue.
MK-2886 is fully side effect free. The only threat is that it's possible to experience some mild natural test shut down in cycles over 4 weeks, but the time between cycles are only 4 weeks.
3.Function
Its Ostarine use:
Increasing lean mass gains
Enhancement for strength
Bodybuiling exercise
Joint healing abilities
Hormone Anabolic raw material (even at doses as low as 3 mg)
For bodybuilding:Enobosarm (Ostarine, MK-2866, GTx-024) - affects both muscle and bone, intended mainly for osteoporosis but also general treatment for andropause and reversing muscle sarcopenia in the elderly and for cachexia in cancer patients
For cutting:Nonsteroidal selective androgen receptor modulator (SARM) used in the treatment of osteoporosis and muscle wasting in animal models. A potential compound for the treatment of hypoactive sexual desire disorder.
For Recomping:Ostarine shines in recomping due to its nutrient portioning results. Calorie is used to build muscle which helps in weight loss and enhancing muscle mass and strength. Suggested dosing is 12.5-25 mg for 4-8 weeks.
4.COA