Description: BPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, Preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, It significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle. FI TC-phalloidin staining was able to demonstrate that BPC 157 induces F-actin formation in fibroblasts. Likewise, Western blot analysis was able to detect the production and activation of paxillin and FAK proteins. The western blot analysis also showed that BPC 157 increases the extent of phosphorylation of paxillin and FAK proteins without affecting the amounts produced. BPC 157 ( Body Protection Compound-157) Is a pentadecapeptide made up of 15 amino acids. The amino acids sequence in BPC 157 is similar to a portion of the human BPC amino acid sequence. Human BPC is found in the gastric juice. Experiments have shown that BPC 157 enhances the healing of wounds, Including tendons wounds such as transected Achilles tendons of rats. The aim of this study was to investigate the probable mechanism that BPC 157 utilizes to accelerate the healing process in an injured tendon. The study used two group of tendon explants of which one group was cultured in a BPC 157-containing medium while the other group was cultured in a medium lacking BPC 157. These cultures were thereafter examined for tendon fibroblasts outgrowths. Such outgrowths indicated tendon regeneration. The results revealed that the explants' Outgrowth was significantly accelerated in the culture containing BPC 157 as compared to the culture lacking BPC 157. Also, A MTT assay did show that BPC 157 does not directly affect cellular proliferation in a culture of rat-derived Achilles tendon. However, Results also showed that BPC 157 significantly increased the survival of cells under oxidative stress. Furthermore, The Transwell filter migration assay showed that BPC 157 significantly increased in-vitro fibroblast migration in a dose-dependent fashion. Moreover, BPC 157 accelerated the dispersal of the fibroblasts in culture dishes in a dose-dependent manner. Applicat ionBPC 157 has a strong anti-inflammatory activity in both acute and chronic inflammation models. In fact, Preliminary results in clinical trials suggest that BPC 157 may become an important therapeutic tool for the treatment of inflammatory bowel disease. BPC 157 was shown to accelerate wound healing and to have a marked angiogenic effect. In addition, It significantly facilitates the healing of bone fracture in rats. This peptide also exhibits an osteogenic effect significantly improving the healing of segmental bone defect. BPC 157 accelerates the healing of transected rat Achilles tendon and transected rat quadriceps muscle. Pentad ecapeptide BPC 157, Composed of 15 amino acids, Is a partial sequence of body protection compound ( BPC) That is discovered in and isolated from human gastric juice. Experimentally it has been demonstrated to accelerate the healing of many different wounds, Including transected rat Achilles tendon. Thi s study was designed to investigate the potential mechanism of BPC 157 to enhance healing of injured tendon. The outgrowth of tendon fibroblasts from tendon explants cultured with or without BPC 157 was examined. Results showed that BPC 157 significantly accelerated the outgrowth of tendon explants. Cell proliferation of cultured tendon fibroblasts derived from rat Achilles tendon was not directly affected by BPC 157 as evaluated by MTT assay. BPC 157-treated cells was significantly increased under the H( 2) O( 2) Stress. BPC 157 markedly increased the in vitro migration of tendon fibroblasts in a dose-dependent manner as revealed by transwell filter migration assay. BPC 157 also dose dependently accelerated the spreading of tendon fibroblasts on culture dishes. The F-actin formation as detected by FITC-phalloidin staining was induced in BPC 157-treated fibroblasts. The protein expression and activation of FAK and paxillin were determined by Western blot analysis, And the phosphorylation levels of both FAK and paxillin were dose dependently increased by BPC 157 while the total amounts of protein was unaltered. 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Product Name | GHRP-6 Acetate |
CAS No. | 87616-84-0 |
Molecular Formula | C46H56N12O6 |
Molecular Weight | 873.01 |
Purity (HPLC) | 98.0%min. |
Appearance | White powder |
Single Impurity (HPLC) | 1.0%max |
Amino Acid Composition | ±10% of theoreticaloreticaloretical |
Peptide Content (N%) | ≥80.0%0.0%0.0% |
Water Content(Karl Fischer) | ≤6.0%6.0%6.0% |
Acetate Content (HPIC) | ≤12.0%2.0%2.0% |
MS(ESI) | Consistent |
Mass Balance | 95.0~105.0% |
Packaging & Shippingppingpping
Packing: 25kg/drum or as your request.
Storage Situation: Stored in a cool and dry well-closed container. Keep away from moisture and strong light/heat.
Shelf Life: Two years when properly stored.
Delivery: Within two weeks after receiving your prepayment.
Filter is an internationally recognized biochemical manufacturing company that specializes in the production of peptide reagents, custom peptides and antibodies is based in Shanghai, China where a 50, 000 square foot headquarter and research facility is located. There are 5 manufacturing sites and 2 Research &Development centers that all together total over 350, 000 square feet. Wet. Wet. We employ over 1000 science professionals with strong Biotech industry backgrounds. Our highly qualified staff which includes over 13 years of Filter management experience and our modern facilities allow Filter is to provide high quality, value-added peptide related products. We support today leading medical researchers all over the world. Products Peptides: Custom peptides , catalogue peptides , pharmaceutical peptides , cosmetic peptides Antibodies: Monoclonal antibody , polyclonal antibody Amino acids and derivates: Unnatural amino acids , N-methyl amino acids , Boc- amino acids and derivates , Fmoc-amino acids and derivates, etc Custom Peptides Filter is able to produce more than 10, 000 purified peptides per month with the help of over 350 synthetic chemists and 250 purification technicians utilizing state-of-the-art highly sophisticated peptide instrumentations. Equipment used includes 400Hz NMR, 2 units of FT-IR, 10 units of MS, Amino Acid Analyzer, 96/102 well automated peptide synthesizers, microwave-assisted peptide synthesizer, 200 units of analytical and preparative HPLC. Global market share has been over 60%for research grade peptides. Filter has become the largest and most recognized custom peptide producer worldwide and continues to experience 10%plus growth every year. Contact Cassie Pan T: 008615294859659 Address: South of Nongye Rd. Zhengdong new District, Zhengzhou Related products | 1 | Abarelix Acetate | 98% | 183552-38-7 |
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| 11 | Bivalirudin Trifluoroacetate | 98% | 128270-60-0 |
| 12 | Buserelin acetate | 98% | 57982-77-1 |
| 13 | Calcuitonin | | 9007/12/9 |
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| 16 | Cerropin B | 98% | |
| 17 | Cetrorelix Acetate | 98% | 130143-01-0 |
| 18 | Cetrorelix Acetate | 98% | 130143-01-0 |
| 19 | CJC-1295 | 98% | 863288-34-0 |
| 20 | Copper Peptide(GHK-Cu) | 98% | 49557-75-7 |
| 21 | CRF (human, rat) Acetate | 98% | 86784-80-7 |
| 22 | CRF (ovine) Trifluoroacetate | 98% | 79804-71-0 |
| 23 | Deslorelin Acetate | 98% | 57773-65-6 |
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| 26 | Elcatonin Acetate | 98% | 60731-46-6 |
| 27 | Eledoisin Acetate | 98% | 69-25-0 |
| 28 | Endothelin-1 Acetate | 98% | 117399-94-7 |
| 29 | Enfuvirtide Acetate (T-20) | 95% | 159519-65-0 |
| 30 | Eptifibatide Acetate | 98% | 148031-34-9/188627-80-7 |
| 31 | Exenatide Acetate | 98% | 141732-76-5 |
| 32 | Felypressin Acetate | 98% | 56-59-7 |
| 33 | Fertirelin Acetate | 98% | 38234-21-8 |
| 34 | Ganirelix acetate | 98% | 123246-29-7 |
| 35 | GHRP-2 Acetate | 98% | 158861-67-7 |
| 36 | GHRP-6 Acetate | 98% | 87616-84-0 |
| 37 | Glatiramer Acetate | 99% | 147245-92-9 |
| 38 | GLP(7-36) | 98% | 107444-51-9 |
| 39 | GLP-1 (7-37) Acetate | 98% | 106612-94-6 |
| 40 | Glucagon Hydrochloride | 98% | 16941-32-5 |
| 41 | Gonadorelin Acetate | 98% | 34973-08-5 |
| 42 | Goserelin Acetate | 98% | 145781-92-6 |
| 43 | GRF (human) Acetate | 98% | 83930-13-6 |
| 44 | Hexarelin Acetate | 98% | 140703-51-1 |
| 45 | Histrelin Acetate | 98% | 76712-82-8 |
| 46 | Icatibant Acetate | 98% | 30308-48-4 |
| 47 | Lanreotide | 98% | 108736-35-2 |
| 48 | Lecirelin (Dalmarelin) Acetate | 98% | 61012-19-9 |
| 49 | Leuprolide | 98% | 74381-53-6 |
| 50 | Leuprorelin Acetate | 98% | 53714-56-0 |
| 51 | Linaclotide Acatate | 98% | 851199-59-2 |
| 52 | Lixisenatide | 98% | 320367-13-3 |
| 53 | Lraglutide | 98% | 204656-20-2 |
| 54 | Lysipressin Acetate | 98% | 50-57-7 |
| 55 | Melanotan II Acetate | 98% | 121062-08-6 |
| 56 | MOG(35-55) | 98% | 163913-87-9 |
| 57 | Nafarelin Acetate | 98% | 76932-56-4 |
| 58 | Nesiritide Acetate (BNP-32) | 98% | 114471-18-0 |
| 59 | Octreotide | 98% | 79517-01-4 |
| 60 | Ornipressin Acetate | 98% | 3397-23-7 |
| 61 | Oxytocin Acetate | 98% | 50-56-6 |
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| 63 | Pexiganan | 98% | 147664-63-9 |
| 64 | Pramlintide Acetate | 98% | 196078-30-5 |
| 65 | Pretirelin | | |
| 66 | PT141 Acetate | 98% | 32780-32-8 |
| 67 | Salmon Calcitonin Acetate | 98% | 47931-85-1 |
| 68 | Secretin Acetate | 98% | 10813-74-8 |
| 69 | Sermorelin Aceta | 98% | 86168-78-7 |
| 70 | Sincalide | 98% | 25126-32-3 |
| 71 | Somatostatin Acetate | 98% | 38916-34-6 |
| 72 | Splenopentin Acetate | 98% | 105184-37-0 |
| 73 | Taltirelin Acetate | 98% | 103300-74-9 |
| 74 | Teriparatide Acetate | 98% | 52232-67-4 |
| 75 | Teriparatide Acetate | 98% | 52232-67-4 |
| 76 | Terlipressin Acetate | 98% | 14636-12-5 |
| 77 | Tetracosactide Acetate | 98% | 16960-16-0 |
| 78 | Thymalfasin | 98% | 62304-98-7 |
| 79 | Thymopentin | 98% | 69558-55-0 |
| 80 | Thymosin α1 AcetateAcetateAcetate | 98% | 14636-12-5 |
| 81 | Thymosin β4 Acetatecetatecetate | 98% | 77591-33-4 |
| 82 | Triptorelin Acetate | 98% | 57773-63-4 |
| 83 | Vapreotide Acetate | 98% | 103222-11-3 |
| 84 | Vasopressin Acetate | 98% | 9034-50-8 |
| 85 | Ziconotide Acetate | 98% | 107452-89-1 |
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