Peptide Steroid Hormone Powders Fragment176-191 GH for Muscle Building

Product Details:

Product name: fragment 176-191
Synonyms: Fragment 177-191, AOD-9604
MF: C78H123N23O23S2
MW: 1815.08152
CAS: 221231-10-3
Appearance: White Powder
Purity: 99%
Grade: Pharmaceutical Grade
Storage: Closed, below 2 ~ 8 C preservation
Usage: AOD-9604 actually acts on the reduction of excessive adipose tissues such as
increase in muscle mass, and enhances the lipid content of the body.

Description:

Growth Steroid peptide fragment 176-191, also known as GH Frag 176-191, is a modified form of amino acids 176-191 of the GH polypeptide. Investigators at Monash University discovered that the fat-reducing effects of GH appear to be controlled by a small region near one end of the Growth Steroid Hormone molecule. This region, which consists of amino acids 176-191, is less than 10% of the total size of the GH molecule and appears to have no effect on growth or insulin resistance. It works by mimicking the way natural Growth Steroid Hormone regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified Growth Steroid Hormone. Like Growth Steroid Hormone, the gH fragment 176-191 stimulates lipolysis (the breakdown or destruction of fat) and inhibits lipogenesis (the transformation of nonfat food materials into body fat) both in laboratory testing and in animals and humans.

GH fragment 176-191 is an analog of the growth Steroid hormone-releasing factor (GRF) which signals the effects of growth Steroid hormone. It is a 15-mer peptide residue of the C-terminus of GH to which tyrosine is added at the N-terminal end. This synthetically produced hormone is very common to weightlifters and bodybuilders because of a number of physical benefits. Studies claimed that it actually acts on the reduction of excessive adipose tissues such as those in the abdominal area, increase in muscle mass, and enhances the lipid content of the body.

These segments of the synthetic peptide gH 176-191 have been investigated for their in vivo effects in laboratory mice musculus. Research results have shown that gH 176-191 have resulted to a short-period increase in blood glucose and a more sustained increase in plasma insulin, together with other fragments such as 172-191, 177-191 and 178-191. In addition, the researchers have suggested that functionality of the peptide depends not only in the informational sequence but should also have the correct physical configuration (Ng and Borstein 1978). Also, this fragment, being a region of high accessibility to proteases and also rich in proline, have been demonstrated to affect the conformational change in the cytoplasmic domain of the band 3 of erythrocyte membrane protein by serving as the hinge for the pivoting of the two subdomains. This then suggest that such residue is significant in conformational changes be serving as sites for peripheral protein binding in some body cells (Low et al. 1984).

Applications:

How much Human Growth Steroid Hormone (GH) Fragment 176-191 should be used?
In most studies favorable results have been shown with dosages between 400-600mcg or 4-6mcg/kg split into multiple dosages per day.

It has been shown that the fat-reducing effects of GH appear to be controlled by a small analog region of the C-terminus end of the GH molecule. This region consists of amino acids 176-191, thus the name. This peptide fragment works by mimicking the way natural GH regulates fat metabolism but without the adverse effects on blood sugar or growth that is seen with unmodified GH. Like unmodified GH, the GH fragment 176-191 stimulates lipolysis and inhibits lipogenesis both en vivo/en vitro. Fragment 176-191 has shown no effect on growth or insulin resistance, unlike the full GH molecule. This is the newest, most powerful GH fragment on the market. Studies have shown sustained fatloss, aimed directly at adipose tissue.

Advantages:

1. We are a professional manufacturer of raw steroid powders from China. Our company has been specialized in this field for many years and won great reputation in all of our customers.
2. Our products have exported to US, Brazil, Canada, Germany, UK, Spain, France, Norway, Romania, Italy, Australia and many other areas. We build long-term cooperation relationship with all of the customers.
3. Could be shipped out within 24 hours after received the payment.
4. High quality, best price, first-class service, high successful delivery rate.

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