Basic Info
Model NO.: 126-07-8
Customized: Non-Customized
Suitable for: Elderly, Children, Adult
Purity: ﹥99%;99%
Sample: Free
Appearance: White Powder
Delivery: Fast and Secure Shipping by EMS, DHL, TNT, FedEx
Trademark: NJBN STEROID
Origin: Made in China
Powder: Yes
Certification: GMP, ISO 9001, USP, BP
State: Solid
Delivery Time: Within 24 Hours Upon Receipt of Payment
Minimum Order Quantity: 10 G
Payment Terms: Western Union, Money Gram, T/T, Bitcoin
Function: Cystic Acne Treatment
Transport Package: 10g/50g/100g/ Foil Bag or 10kg/25kg/ Drum
Product Description
Antifungal 98% Antibiotics Pharmaceutical Intermediate CAS 126-07-8 (+)-Griseofulvin
1. Quick Detail of (+)-Griseofulvin
Product name | (+)-Griseofulvin |
Other Name | (+)-GRISEOFULVIN;GRISEOFULVIN;[2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE;(2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE;7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE;(+)-griseofulvi;(2s-trans)-7-chloro-2',4,6-trimethoxy-6'-methylspiro[benzofuran-2(3h),1'-[2]cy;(2s-trans)-xy-6'-methyl |
Original | China |
CAS | 126-07-8 |
ENIECS | 204-767-4 |
Molecular formula | C17H17ClO6 |
Brand name | NJBNSteroid |
Leading time | within 24 hours upon receipt of payment |
Delivery | Fast and secure shipping by EMS, DHL, FedEx, UPS |
Purity | 99% |
Package | Discreet and Hidden package according to specific requirement |
Appearance | White Powder |
Certification | SGS, ISO 9001, KOSHER |
Payment Terms | Western Union, Money Gram , T/T, Bitcoin |
Minimum Order Quantity | 10g |
Price | Negotiable |
Usage | Antifungal and Antibiotics |
Description of (+)-Griseofulvin
Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.
(+)-Griseofulvin Applications
Griseofulvin is a non-polyene class antifungal antibiotics; it can strongly inhibit the mitosis of fungal cell and interfere with the fungal DNA synthesis; it can also bind to tubulin to prevent fungal cell division.
It has been applied to clinical medicine since 1958 and has currently been widely used for treating the fungal infections of the skin and the stratum corneum with strong inhibitory effects on Trichophyton rubrum and Trichophyton tonsorans, etc.
Griseofulvin is not only a widely used antibiotic for clinical treatment of fungal infections of the skin and cuticle, but also applied in agriculture for prevention and treatment of fungal diseases; for example, it has a special efficacy on treating a kind of candidiasis in apple which can cause infection during pollination.
Usage:
This product mainly has good antibacterial effect against Trichophyton, Microspores, and Epidermophyton fungi. However, it has no anti-bacterial effect on Candida, Cryptococcus, Histoplasma, Sporothrix, Blastomyces, and Coccidioides and so on. Mechanism of action of is drug is through interfering with the biosynthesis of nucleic acids of fungal and further inhibiting of its growth.
This product is suitable for the treatment of a variety of ringworm, including tinea capitis, tinea barbae, body tinea, jock itch, foot tinea and onychomycosis. The various kinds of tinea mentioned are caused by various fungi including Trichophyton rubrum, Trichophyton tonsorans, Trichophyton mentagrophytes, Fingers Trichophyton, etc., and Microsporon audouini, Microsporon canis, Microsporon gypseum and Epidermophyton floccosum, etc. due.
This product is not suitable for treatment in mild cases, localized infection cases and cases which can be treated with topical antifungal agents. Griseofulvin is not effective in treating the infections of a various kinds of fungi such as Candida, Histoplasma, Actinomyces, Sporothrix species, Blastomyces, Coccidioides, Nocardio and Cryptococcus species as well as treating tinea versicolor.
It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum
Technical Test Sheet
Test Items | Specification | Test Results |
Characteristics | A yellowish-white,microfine powder | yellowish-white,microfine powder |
Melting point | 220ºC About 220ºC 220ºCrdm;C 220ºC | 218.4ºC-219.4ºC19.4ºCrdm;C19.4ºC |
Specific optical rotation | +354o~+364o | +356o |
Identification | Meets the requirements | Meets the requirements |
Check-up Particles size | Meets the requirements | Meets the requirements |
Acidity | 0.25g consumed 0.02mol/l NaOH not more intensely coloured than reference solution Y4 | 0.6ml |
Clarity and colour of solution | The solution is clear and not more intensely coloured than reference solution Y4 | Y5~Y6 Clear Y5~Y6 |
Matter soluble in petroleum spirit | ≤0.2%0.2%0.2% | 0.1% |
Sulphated ash | ≤0.2%0.2%0.2% | 0.1% |
Related substances | -Cl:<0.60 -H<0.15lt;0.15 | -Cl:0.48-H:0.04 |
Loss on drying | ≤1.0%1.0%1.0% | 0.1% |
Abnormal toxicity | Meets the requirements | Meets the requirements |
assay(on the anhydrous substance) | 97.0%~102.0% | 98.3% |
Conclusion | The above certificate of analysis is in compliance with BP/EP,meets the standard requirements. |
How to Complete an Order?
Make an order | 1.Please let me know the items you are looking for, quantity, and the destination country; |
2.You confirm all details, and offer us purchasing order; |
3.We send the detail price of our product and offer the suitable shipping method for reference; |
4.You confirm the order and pay money 100% in advance and send us the detail address. |
5.We arrange the shipment according to your requirements. |
6.We offer after-sales service after you receive parcel. |
Shipping | Provide your addressee info. ( phone number , zip code ) |
Packing | According to different countries and quantity of orders |
Lead Time | Arranged within 24 hours upon receipt of your payment |
Photos | Photos of parcel would be offered to tell apart the steroids in advance |
Delivery Time | Usually 4-6 working days to reach destinations |
Tracking number | Offered once it is released on the Net .Normally within 24hours upon the receipt of payment. |
After-sale service | 24/7 online for problems and concern related to the product |
Our promise
1.High quality and standard:
Standard: Enterprise Standard;
All Purity≥98%;98%;98%;
We are manufacturer and can provide high quality products with factory price.
2. Fast and safe delivery:
Parcel can be sent out within 24 hours after payment. Tracking number is available;
Secure and discreet shipment (EMS , DHL , TNT , FedEx , UPS). Various transportation methods for your choice;
Customs pass rate ≥99%;99%;99%;
We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.
3.Service:
Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
Flexible payment terms (Western Union , Money Gram , T/T , Bitcoin) makes you convenient at payment choice.