Product name :Nicotinamide
Synonym:Niacinamide,Vitamin B3,Vitamin PP
Molecular formula :C6H6N2O
CAS:98-92-0
Molecular weight:122.12
Melting point :128~131°C
Solubility: 1g is soluble in 2ml water/1.5ml ethanol /10ml glycerin. It's easily soluble in acetone, amyl alcohol, chloroform, propylene glycol, butanol. It is almost insoluble in ether and benzene.
Description:
White crystalline powder or white granular powder; odorless or near odorless, bitter taste.
Functions and applications:
As a structured form of vitamins B, Nicotinamide is an important component of coenzyme I and II in the body of both human and animals.
In feed additives field:
1.Preventing the skin diseases and the diseases of alimentary canal;
2.Promoting animal's growth, improving egg yield and hatching rates, ensuring good feathers;
3.Cure for mucosal inflammation and ulcers;
4.Preventing perosis of animals:
Lack of nicotinamide in animal's body will cause the poultry's skin disease, feather decrease and dermatitis. For pig, will cause hair shedding, dermatitis, and inflammation of tongue, esophageal mucosa and space inside mouth, such as black-tongue. And will also cause disorder of digestive system ,such as vomiting, diarrhea and decrease of food intake, neurological disorders, muscle spasm and paralysis, back ankle hypertrophy (especially for poultry ), and perosis.
In food additives and medicine field:
1.Preventing skin disease and diseases of alimentary canal, such as pellagra, dermatitis,black-tongue, vomiting and diarrhea,etc;
2.Promoting substance and energy's metabolism in body, promoting body's growth in normal;
3.Cooperating with other medicine used to treat various mucosal inflammation and ulcers;
4.Strong effect on vasodilatation, improving supplying of blood, it also has a certain effect on cerebral thrombosis, coronary heart disease and hyperlipidemia;
5.Supplementing the lacking of niacin and nicotinamide due to long-term taking isoniazid and analogues.
In daily cosmetics field:
In recent years, nicotinamide is widely applied in cosmetics. 2% dosage of nicotinamide are used in the basic cream for skin whitening and anti-wrinkling.
In Shampoo & Conditioner, it will be stimulating hair follicle, improving follicle's blood circulation so as to prevent trichomadesis.
In addition, because nicotinamide has the function on vasodilatation, it can also be used in the products for removing the dark circles around eyes.
Specifications:
Item
CP2005
USP31
BP2009
EP6.0
Appearance
White crystal power
Assay%
≥98.5
98.5~101.5
99.0~101.0
99.0~101.0
Melting point°C
128 ~131
128 ~131
128 ~131
128 ~131
PH
5.5~7.5
-
6.0~7.5
6.0~7.5
Loss on drying% ≤
0.5
0.5
0.5
0.5
Residue on ignition % ≤
0.1
0.1
0.1
0.1
Heavy metal (as Pb)% ≤
0.002
0.003
0.003
0.003
As feed additives:
Item
Index
Appearance
White crystal powder or granulated powder
Assay
≥99.0%
Melting point
128.0~131.0°C
PH(10% Aq. solution)
5.5~7.5
Water
≤0.1%
Residue on ignition
≤0.1%
Heavy metal (as Pb)
≤0.002%