Product Name:
CidofovirAlso Name: PMPC; GS-504; Vistide; (S)-HPMPC
Assay: 99%
CAS No.: 113852-37-2
Usages: Anti-viral
Descriptions:
Cidofovir is an injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. It is an acyclic nucleoside phosphonate, and is therefore independent of phosphorylation by viral enzymes, in contrast to, for instance, acyclovir.
Functions:
Cidofovir demonstrated a statistically significant effect in delaying the progression of CMV retinitis lesions in newly diagnosed patients, as well as in previously treated patients who had failed other therapies.
Cidofovir has also shown efficacy in the treatment of acyclovir resistant herpes
Cidofovir has also been investigated as a treatment for progressive multifocal leukoencephalopathy.
Cidofovir shows anti-BK virus activity in a subgroup of transplant patients.
Cidofovir is being investigated as a complementary intralesional therapy against papillomatosis caused by HPV
| Product Name | Cidofovir |
| Synonym | PMPC;GS-504;Vistide;(S)-HPMPC |
| CAS Number | 113852-37-2 |
| Molecular Formula | C8H14N3O6P |
| Molecular Weight | 279.19 |
| Purity | 99% |
| Appearance | White or off-white crystalline powder |