Yohimbine Hydrochloride

CAS:65-19-0

MF:C21H27ClN2O3

MW:390.9

EINECS:200-600-4

Synonyms:17-HYDROXYYOHIMBAN-16-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE;17A-HYDROXYYOHIMBAN-16A-CARBOXYLIC ACID METHYL ESTER HYDROCHLORIDE;YOHIMBE HCL;YOHIMBINE HCL;YOHIMBINE HYDROCHLORIDE;QUERBRACHINE;17alpha)-alph ;antagonil

Properties

Melting point:288-290 °C (dec.)(lit.)

alpha 99 º (c=1%, H2O, dry subst)

refractive index 103 ° (C=1, H2O)

storage temp. Refrigerator

solubility H₂O: 10 mg/mL

form powder

color white to off-white

Sensitive Light Sensitive

Merck 14,10102

Safety Information

Symbol(GHS)

Indications and Uses

Yohimbine hydrochloride is indicated as a sympathicolytic and mydriatic. It may have activity as an aphrodisiac.

Impotence (not able to have erections):

The way yohimbine works is not known for sure. It is thought, however, to work by increasing the body's production of certain chemicals that help produce erections. It does not work in all men who are impotent.

New research that shows it could be an herb with very effective antioxidant potential. Research shows it is a vasodilator, which means that it increases blood flow to the extremities and appendages.

Applications

Increase muscular tension or urinary function no damage sex; Accelerate human body energy metabolism, increase energy supply.It is sold as prescription medicine in pure form for the treatment of sexual dysfunction. Yohimbine was explored as a remedy for type 2 diabetes in animal and human models carrying polymorphisms of the α2A-adrenergic receptor gene.

Yohimbine has been shown in human studies to be effective in the treatment of male impotence. Yohimbine has been shown to be effective in the treatment of orgasmic dysfunction in men. Yohimbine has also been used to treat hypoactive sexual desire disorder (reduced libido) in women.

Yohimbine has been used to facilitate recall of traumatic memories in the treatment of post traumatic stress disorder (PTSD). Use of yohimbine outside therapeutic settings may not be appropriate for persons suffering from PTSD. In pharmacology, yohimbine is used as a probe for α2-adrenoceptor. In veterinary medicine, yohimbine is used to reverse anesthesia from the drug xylazine in small and large animals.

Function of Yohimbine Hydrochloride

a.Yohimbine Hydrochloride is shown to be a powerful antioxidant.
b.Yohimbine Hydrochloride is an aphrodisiac for both men and women.
c.Yohimbine Hydrochloride also helps prevent arteries from getting clogged.
d.Yohimbine Hydrochloride has also been shown to help prevent heart attacks.
e.Yohimbine Hydrochloride is decreasing fat synthesis and working as a great anti-depressant.
f.Yohimbine Hydrochloride can also elevate mood, reduce anxiety and depression,and helps building muscles.
g.Recent studies suggest Yohimbine Hydrochloride may be effective in the treatment of male impotence especially that associated with diabetes.
COA

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