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Mifepristone blocks a hormone required to sustain the pregnancy. Typically it is followed two days
later by another medicinal, misoprostol, to induce contractions, and the pregnancy is terminated.
Mifepristone is also know as RU486. The FDA has approved Mifepristone for use in the United
States. Mifepristone has been used extensively in France and several other countries. Over half a
million woman have had a medical abortion using Mifepristone.
Application:
Mifepristone plays a role on the receptor level of new antifertility drugs, no progesterone,
androgen, estrogen activity.It has an effect on softening and dilating uterine neck. It is a new anti -
progesterone, and anti-glucocorticoid activity, without progesterone, estrogen, androgen and
estrogen activity. And progesterone receptor affinity is 5 times stronger than progesterone. For
termination of early pregnancy, reinstating menstruation and terminating pregnancy, fetal death,
etc. in induction of labor.
Mifepristone action principle that by blocking the progesterone receptor and the production of
anti-pregnancy role, the effects and has been widely used clinically. Mifepristone and
prostaglandin drugs used, can be used to terminate an early pregnancy amenorrhea within 49d.
Usage of a total of 150mg of mifepristone Dayton clothing or in divided doses, the first paragraph
4d 3d or oral misoprostol 600ug, abortion drug application, greatly reducing the complications
caused by abortions, reducing the majority suffering women of childbearing age.
Lab Test Result:
Test Items | Standard | Results | |
Description | Light yellow crystalline powder | Conform | |
Melting Point | 192ºC~196ºC | Conform | |
Specific Rotation | +124°~ +129° | +127.1° | |
Related substances | (Single):≤0.5% | 0.31% | |
(Total):≤1.0% | 0.59% | ||
Loss On Drying | ≤0.5% | 0.1% | |
Assay | ≥98.5% | 99.5% | |
Sieve analysis | ≤30¦Ìm | Conform | |
Conclusion | The specification conforms to CP 2010 standard |
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