Description:

Melatonin is a hormone secreted by the pineal gland, and its chemical structure was 5- methoxy -

N- acetyl tryptamine, the physiological function of inhibiting gonad, thyroid, adrenal gland,

parathyroid gland and pituitary function, inhibit precocious puberty, reduce pituitary Melanotropin

secretion; and has a central nervous system function, can improve the convulsion the threshold,

cause drowsiness. When pinealectomy after the animal experiment showed hyperplasia of the

glands, weight increase, especially sex and sexual organs of immature rats early, pituitary

secretion of LH and FSH increased, increasing secretion of thyroid and adrenal cortex hormone

melatonin. More reduced pituitary MSH and whiten the skin of this role. Effects on the central

nervous system, in the human EEG showed slow rhythm, increased seizure threshold, sleepiness,

but does not affect their behavior and personality, of temporal lobe epilepsy and Ba Jinsen

disease can reduce the motor nerve Abnormal EEG changes.

Application:

1. Melatonin can be used as medicine health care products, so as to enhance people's immune

function, preventing aging and back to youth. What's more, it is also a kind of natural 'sleeping

pill'.

2. Melatonin is a kind of hormone secreted by pineal body of pituitary gland in the body. The

amount of melatonin has something to do with light. The weaker the light is, the more the

melatonin is, whereas the less. In addition, it is helpful to one's sleep.

3. Biochemical research.

Usage:

1. sleep induction, modifies circadian rhythm, antioxidant, free radical scavenger

2. Immunostimulant;Melatonin receptor ligand

3. Hormone; mediates photoperiodicity in mammals; inhibits cerebellar nitric oxide synthetase;

peroxynitrite scavenger. Melatonin has complex effects on apoptotic pathways, inhibiting

apoptosis in immune cells and neurons but enhancing apoptotic cell death of cancer cells. Inhibits

proliferation/metastasis of breast cancer cells by inhibiting estrogen receptor action.

4. Hormone postulated to mediate photoperiodicity in mammals. Inhibits cerebellar nitric oxide

synthetase

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