99% White Crystalline Powder Lidocaine with EP 8.0 Standard
Lidocaine Hydrochloride
Alias: Lidocaine HCl; Lidocaine Hydrochloride; Lidocaine; Xylocaine
CAS: 73-78-9
EINECS: 200-803-8
Molecular Formula: C14H23ClN2O
Molecular Weight: 270.8
Melting Point: 80-82°C
Assay: 99%
Packaging: 25kg/ drum
Properties: This product is a white crystalline powder; Odorless, bitter taste, the numbness.
Usage: Local anesthetic, antiarrhythmic drug, used for a variety of anesthesia and rapid ventricular arrhythmia.
Lidocaine - Clinical Pharmacology

Mechanism of action:

Lidocaine stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the initiation and conduction of impulses, thereby effecting local anesthetic action.

Hemodynamics:

Excessive blood levels may cause changes in cardiac output, total peripheral resistance, and mean arterial pressure. With central neural blockade these changes may be attributable to block of autonomic fibers, a direct depressant effect of the local anesthetic agent on various components of the cardiovascular system and/or the beta-adrenergic receptor stimulating action of epinephrine when present. The net effect is normally a modest hypotension when the recommended dosages are not exceeded.

Pharmacokinetics and metabolism:

Information derived from diverse formulations, concentrations and usages reveals that Lidocaine is completely absorbed following parenteral administration, its rate of absorption depending, for example, upon various factors such as the site of administration and the presence or absence of a vasoconstrictor agent. Except for intravascular administration, the highest blood levels are obtained following intercostal nerve block and the lowest after subcutaneous administration.

Indications and Usage for Lidocaine:

Lidocaine Hydrochloride Injection, USP is indicated for production of local or regional anesthesia by infiltration techniques such as percutaneous injection and intravenous regional anesthesia by peripheral nerve block techniques such as brachial plexus and intercostal and by central neural techniques such as lumbar and caudal epidural blocks, when the accepted procedures for these techniques as described in standard textbooks are observed.

Contraindications:

Lidocaine is contraindicated in patients with a known history of hypersensitivity to local anesthetics of the amide type.

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Product Tags:

local anesthesia drugs

pain killer powder

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