Basic Information:

Alias: Orlipastat; (-)-TETRAHYDROLIPSTATIN;
ORLISTAT

Chemical Properties: Off-White Solid.

Usage: An antiobesity agent. A pancreatic lipase inhibitor. Antiobesity agent. Antidiabetic. Orlistat is an antiobesity agent. Orlistat is an pancreatic lipase inhibitor.
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Description:
Tetrahydrolipstatin (orlistat) is a semi-synthetic derivative of lipstatin, a metabolite isolated from Streptomyces toxytricini. Tetrahydrolipstatin acts as a potent, irreversible inhibitor of pancreatic lipase. In vivo, it blocks the absorption of triglycerides while allowing fatty acid absorption. Tetrahydrolipstatin is widely used for the treatment of obesity.

Orlistat Usage:
1. Orlistat is a drug designed for obesity treatment, is internationally recognized as a new type of lipid-lowering drugs to lose weight.
2. it primary function is preventing the absorption of fats from the human diet by acting as a lipase inhibitor, thereby reducing caloric intake. It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet
3. Orlistat is the saturated derivative of lipstatin, a potent natural inhibitor of pancreatic lipases isolated from the bacterium Streptomyces toxytricini.However.
4. Due to its relative simplicity and stability, orlistat was chosen over lipstatin for development as an anti-obesity drug.