Quick Details:

CAS NO.: 171596-29-5

Appearance: White Crystalline Powder

Assay: 98%

Molecular Formula:C22H19N3O4

Molecular Weight:389.341

Storage: Shading, Confined Preservation

Tadalafil (Tadalifil citrate), a phosphodiesterase type 5 inhibitor, is used to treat erectile dysfunction (ED) and decreased libido in males. Tadalafil works by aiding relaxation of blood vessels and increasing blood flow in the penis during sexual arousal, resulting in improved erectile function. Tadalafil is much longer lasting. Effects can be felt anywhere between 36-48 hours.

Action: Tadalafil improves erectile function significantly, possibly increased sexual activity, and is very safe.

There are limited side effects associated with its use. The most common side effects are headache, upset stomach, back pain, and muscle aches, and usually subside with in a few hours.Tadalafil was also found to be significantly higher at the end of the month, due to increased sexual activity.

Descriptions:

Tadalafil is guanosine monophosphate (cGMP) specific phosphodiesterase type 5 (PDE5) selective, reversible inhibitor, when stimulation leads to local release of nitric oxide, PDE5 inhibition by tadalafil, to improve the level of intracavernous cGMP, which leads to smooth muscle relaxation, blood flows into the penile tissue, produce an erection, such as sexual stimulation.

Although all work by inhibiting PDE5, tadalafil's pharmacologic distinction is its longer half-life (17.50 hours) - compared to sildenafil (4.0-5.0 hours) and vardenafil (4.0-5.0 hours) - resulting in longer duration of action, and so partly responsible for 'The Weekend Pill' sobriquet.

Furthermore, the longer half-life is the basis for current investigation of tadalafil's daily therapeutic use in relieving pulmonary arterial hypertension. Sildenafil is approved in several world regions as a thrice-daily therapy for pulmonary arterial hypertension.

Applications:

Like its predecessor Viagra, Cialis is used to treat erectile dysfunction in men. One of the more embarrassing side effects of post-cycle-therapy is the decreased libido caused by the sudden absence of exaggerated testosterone levels in the body, often leading to ED.

Tadalafil is used to treat male sexual function problems (impotence or erectile dysfunction) by blocking a certain enzyme (phosphodiesterase-PDE5) in the body. In combination with sexual stimulation, tadalafil helps blood flow into the penis to achieve and maintain an erection.

Tadalafil is also used in both men and women to treat the symptoms of pulmonary arterial hypertension. This is high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs. When the smaller blood vessels in the lungs become more resistant to blood flow, the right ventricle must work harder to pump enough blood through the lungs.

Usages:

Like its predecessor Viagra, Cialis is used to treat erectile dysfunction in men. One of the more embarrassing side effects of postcycletherapy is the decreased libido caused by the sudden absence of exaggerated testosterone levels in the body, often leading to ED. If you cann't get it up after your cycle, get the pill.