Lidocaine Hydrochloride for Pain Killer CAS No.:73-78-9

Lidocaine Hydrochloride for Pain Killer CAS No.:73-78-9

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Quick Detail:


Product nameLidocaine Hydrochloride
Other nameLidocaine HCL
CAS73-78-9
MFC14H23ClN2O
MW;270.7982
Molecular structure
Assay99%
Appearance:White crystalline powder;
Usagesoluble in water or ethanol,dissolved in chloroform, insoluble in ether.

Description:

Lidocaine, as a local anesthetic, is characterized by a rapid onset of action and intermediate duration of efficacy. Therefore, lidocaine is suitable for infiltration, block and surface anesthesia. Longer-acting substances such as bupivacaine are sometimes given preference for subdural and epidural anesthesias. lidocaine, on the other hand, has the advantage of a rapid onset of action. It can stop Epinephrine vasoconstricts arteries form bleeding, and it can also delays the resorption of lidocaine, almost doubling the duration of anaesthesia. For surface anesthesia several formulations are available that can be used e.g. for endoscopies, before intubations etc. Buffering the pH of lidocaine makes local freezing less painful. Lidocaine drops can be used on the eyes for short ophthalmic procedures.

how does it work?

Lidocaine works by temporarily blocking this pathway of pain signals along nerves. It does this by stopping the sodium entering the nerve ending at the site of the pain. This prevents an electrical signal building up and passing along the nerve fibres to the brain.


Lidocaine injection is also used in the emergency treatment of heart rhythm disturbances, particularly in cases of suspected or proven heart attack. It is given by intravenous infusion or intravenous bolus injection.Lidocaine is a type of medicine called a local anaesthetic. It is used to numb areas that would otherwise feel pain.


Pain is caused by the stimulation of pain receptors at the ends of nerves. The stimulation causes sodium to enter the nerve ending, which causes an electrical signal to build up in the nerve. When this electrical signal is big enough, it passes along the nerve to the brain, where the signal is interpreted as pain.


Application:


Lidocaine Hydrochloride contains the active ingredient lidocaine hydrochloride (previously known

as lignocaine hydrochloride ).Lidocaine is a type of medicine called a local anaesthetic. It is used

to numb areas that would otherwise feel pain.Pain is caused by the stimulation of pain receptors

at the ends of nerves.


The stimulation causes sodium to enter the nerve ending, which causes an

electrical signal to build up in the nerve. When this electrical signal is big enough, it passes along

the nerve to the brain, where the signal is interpreted as pain.


Lidocaine HCL works by temporarily blocking this pathway of pain signals along nerves. It does

this by stopping the sodium entering the nerve ending at the site of the pain. This prevents an

electrical signal building up and passing along the nerve fibres to the brain.Lidocaine injection is

also used in the emergency treatment of heart rhythm disturbances, particularly in cases of

suspected or proven heart attack. It is given by intravenous infusion or intravenous bolus injection.


Lidocaine HCI Test Report(COA):


ItemStandardResult
CharacteristicsA white or almost white crystalline powderConform
IdentificationShould meet related requirementsConform
Appearance of solutionShould meet related requirementsPassed
PH3.5-5.54.5
Specific optical rotation+135~+150+143
Boiling point350.8 C at 760 mmHgConform
Flash point166 CConform
Lincomycin B5.0% max2.9%
Heavy metals5ppm maxConform
Residue on ignition0.5% max0.1%
Water3.1-4.6%4.3%
Bacterial endotoxinssmaller than 0.5IU/mgsmaller than0.5IU/mg
AssayNot less than 89.5% and not more than 102.0% of lincomycin (C18H35ClN2O6S))99.5%